Structure and transport mechanism of the human cholesterol transporter ABCG1.

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第一作者： Da,Xu

第一单位： Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230027, China.

作者： Da,Xu ^[1] ; Yanyan,Li ^[2] ; Fengrui,Yang ^[3] ; Cai-Rong,Sun ^[1] ; Jinheng,Pan ^[2] ; Liang,Wang ^[1] ; Zhi-Peng,Chen ^[1] ; Shu-Cheng,Fang ^[1] ; Xuebiao,Yao ^[3] ; Wen-Tao,Hou ^[4] ; Cong-Zhao,Zhou ^[5] ; Yuxing,Chen ^[6]

作者单位： Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230027, China. ^[1] Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang 310024, China. ^[2] MOE Key Laboratory for Cellular Dynamics, University of Science and Technology of China, Hefei, Anhui 230027, China. ^[3] Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230027, China. Electronic address: todvince@mail.ustc.edu.cn. ^[4] Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230027, China. Electronic address: zcz@ustc.edu.cn. ^[5] Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230027, China. Electronic address: cyxing@ustc.edu.cn. ^[6]

关键词 ABC transporter atherosclerosis cholesterol cryo-EM human ABCG1 reverse cholesterol transport sphingomyelin

主题词胆固醇(Cholesterol);冷冻电子显微镜检查(Cryoelectron Microscopy);人类(Humans);鞘磷脂类(Sphingomyelins)

DOI 10.1016/j.celrep.2022.110298

PMID 35081353

发布时间 2022-02-14

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