Structural and mechanistic basis of reiterative transcription initiation.

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作者： Yu,Liu ^[1] ; Libing,Yu ^[2] ; Chirangini,Pukhrambam ^[1] ; Jared T,Winkelman ^[2] ; Emre,Firlar ^[2] ; Jason T,Kaelber ^[3] ; Yu,Zhang ^[1] ; Bryce E,Nickels ^[2] ; Richard H,Ebright ^[3]

作者单位： Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ 08854. ^[1] Waksman Institute of Microbiology, Rutgers University, Piscataway, NJ 08854. ^[2] Department of Genetics, Rutgers University, Piscataway, NJ 08854. ^[3] Rutgers CryoEM and Nanoimaging Facility, Institute for Quantitative Biomedicine, Rutgers University, Piscataway, NJ 08854. ^[4] Key Laboratory of Synthetic Biology, CAS Center for Excellence in Molecular Plant Sciences, Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 200032, China. ^[5] Waksman Institute of Microbiology, Rutgers University, Piscataway, NJ 08854; bnickels@waksman.rutgers.edu ebright@waksman.rutgers.edu. ^[6] Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ 08854; bnickels@waksman.rutgers.edu ebright@waksman.rutgers.edu. ^[7]

关键词 DNA scrunching RNA polymerase reiterative transcription initiation transcription transcriptional slippage

主题词 DNA(DNA);指导DNA的RNA聚合酶类(DNA-Directed RNA Polymerases);启动区, 遗传(Promoter Regions, Genetic);RNA(RNA);转录启动子(Transcription Initiation Site);转录, 遗传(Transcription, Genetic)

DOI 10.1073/pnas.2115746119

PMID 35082149

发布时间 2022-07-27

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