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Forskolin-induced organoid swelling is associated with long-term cystic fibrosis disease progression.

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第一作者: Danya,Muilwijk
第一单位: Dept of Pediatric Respiratory Medicine, Wilhelmina Children's Hospital, University Medical Center, Utrecht University, Utrecht, The Netherlands.;These authors contributed equally to this work.
作者单位: Dept of Pediatric Respiratory Medicine, Wilhelmina Children's Hospital, University Medical Center, Utrecht University, Utrecht, The Netherlands.;These authors contributed equally to this work. [1] Dept of Pediatric Respiratory Medicine, Wilhelmina Children's Hospital, University Medical Center, Utrecht University, Utrecht, The Netherlands.;Regenerative Medicine Utrecht, University Medical Center, Utrecht University, Utrecht, The Netherlands.;These authors contributed equally to this work. [2] Dept of Pediatric Respiratory Medicine, Wilhelmina Children's Hospital, University Medical Center, Utrecht University, Utrecht, The Netherlands. [3] Dept of Pediatric Respiratory Medicine, Wilhelmina Children's Hospital, University Medical Center, Utrecht University, Utrecht, The Netherlands.;Regenerative Medicine Utrecht, University Medical Center, Utrecht University, Utrecht, The Netherlands. [4] Dept of Pediatric Respiratory Medicine, Wilhelmina Children's Hospital, University Medical Center, Utrecht University, Utrecht, The Netherlands.;Regenerative Medicine Utrecht, University Medical Center, Utrecht University, Utrecht, The Netherlands.;Center for Lysosomal and Metabolic Diseases, Dept of Clinical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands. [5] Dept of Pulmonology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands. [6] Haga Teaching Hospital, The Hague, The Netherlands. [7] Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands. [8] Maastricht University Medical Center, Maastricht, The Netherlands. [9] Amsterdam University Medical Center, location AMC, Amsterdam, The Netherlands. [10] University of Groningen, University Medical Center Groningen, Beatrix Children's Hospital, Department of Pediatric Pulmonology and Pediatric Allergology, Groningen, The Netherlands.;University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands. [11] Hubrecht Organoid Technology (HUB), Utrecht, The Netherlands. [12] Dutch Cystic Fibrosis Foundation (NCFS), Baarn, The Netherlands. [13] Dept of Data Science and Biostatistics, Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht University, Utrecht, The Netherlands. [14] Dept of Pediatric Respiratory Medicine, Wilhelmina Children's Hospital, University Medical Center, Utrecht University, Utrecht, The Netherlands.;C.K. van der Ent and J.M. Beekman contributed equally to this article as lead authors and supervised the work. [15] Dept of Pediatric Respiratory Medicine, Wilhelmina Children's Hospital, University Medical Center, Utrecht University, Utrecht, The Netherlands J.Beekman@umcutrecht.nl.;Regenerative Medicine Utrecht, University Medical Center, Utrecht University, Utrecht, The Netherlands.;Center for Living Technologies, University Medical Center, Utrecht, The Netherlands.;C.K. van der Ent and J.M. Beekman contributed equally to this article as lead authors and supervised the work. [16]
DOI 10.1183/13993003.00508-2021
PMID 35086832
发布时间 2022-09-13
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