Modulating Nanoparticle Size to Understand Factors Affecting Hemostatic Efficacy and Maximize Survival in a Lethal Inferior Vena Cava Injury Model.

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作者： Celestine,Hong ^[1] ; Osaid,Alser ^[2] ; Anthony,Gebran ^[2] ; Yanpu,He ^[3] ; Wontae,Joo ^[1] ; Nikolaos,Kokoroskos ^[2] ; George,Velmahos ^[2] ; Bradley D,Olsen ^[1] ; Paula T,Hammond ^[1]

作者单位： Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.;Institute for Soldier Nanotechnologies, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States. ^[1] Division of Trauma, Emergency Surgery and Surgical Critical Care, Department of Surgery, Massachusetts General Hospital & Harvard Medical School, Boston, Massachusetts 02144, United States. ^[2] Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States. ^[3]

关键词 hemostasis internal injury nanoparticle noncompressible hemorrhage particle size platelet

主题词止血(Hemostasis);止血药(Hemostatics);纳米粒子(Nanoparticles);粒子大小(Particle Size);组织分布(Tissue Distribution);腔静脉, 下(Vena Cava, Inferior)

DOI 10.1021/acsnano.1c09108

PMID 35090344

发布时间 2024-09-14

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