Microfluidic Squeezing Enables MHC Class I Antigen Presentation by Diverse Immune Cells to Elicit CD8<sup>+</sup> T Cell Responses with Antitumor Activity.-论文-万方医学网

第一作者： Matthew G,Booty

第一单位： SQZ Biotechnologies, Watertown, MA.

作者： Matthew G,Booty ^[1] ; Kelan A,Hlavaty ^[1] ; Adam,Stockmann ^[1] ; Emrah Ilker,Ozay ^[1] ; Carolyne,Smith ^[1] ; Lina,Tian ^[1] ; Edylle,How ^[1] ; Disha,Subramanya ^[1] ; Anita,Venkitaraman ^[1] ; Christian,Yee ^[1] ; Olivia,Pryor ^[1] ; Kelly,Volk ^[1] ; Katarina,Blagovic ^[1] ; Ildefonso,Vicente-Suarez ^[1] ; Defne,Yarar ^[1] ; Melissa,Myint ^[1] ; Amy,Merino ^[1] ; Jonathan,Chow ^[1] ; Tarek,Abdeljawad ^[1] ; Harry,An ^[1] ; Sophia,Liu ^[2] ; Shirley,Mao ^[2] ; Megan,Heimann ^[2] ; LeeAnn,Talarico ^[1] ; Miye K,Jacques ^[1] ; Eritza,Chong ^[1] ; Lucas,Pomerance ^[1] ; John T,Gonzalez ^[1] ; Ulrich H,von Andrian ^[3] ; Klavs F,Jensen ^[2] ; Robert,Langer ^[4] ; Hendrik,Knoetgen ^[5] ; Christine,Trumpfheller ^[6] ; Pablo,Umaña ^[6] ; Howard,Bernstein ^[1] ; Armon,Sharei ^[1] ; Scott M,Loughhead ^[7]

作者单位： SQZ Biotechnologies, Watertown, MA. ^[1] Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA. ^[2] Department of Immunology, Harvard Medical School, Boston, MA.;Ragon Institute of MGH, MIT, and Harvard, Boston, MA.;Center for Immune Imaging at Harvard Medical School, Boston, MA. ^[3] Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA.;David Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA. ^[4] Roche Innovation Center Basel, Roche Pharmaceutical Research and Early Development, Basel, Switzerland; and. ^[5] Roche Innovation Center Zurich, Roche Pharmaceutical Research and Early Development, Schlieren, Switzerland. ^[6] SQZ Biotechnologies, Watertown, MA; scott.loughhead@sqzbiotech.com. ^[7]

主题词过继转移(Adoptive Transfer);动物(Animals);抗原呈递(Antigen Presentation);抗原呈递细胞(Antigen-Presenting Cells);抗原, 肿瘤(Antigens, Neoplasm);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);细胞培养技术(Cell Culture Techniques);女(雌)性(Female);组织相容性抗原Ⅰ类(Histocompatibility Antigens Class I);人类(Humans);免疫法(Immunization);免疫表型分型(Immunophenotyping);白细胞, 单核(Leukocytes, Mononuclear);淋巴细胞, 肿瘤浸润(Lymphocytes, Tumor-Infiltrating);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);微流体学(Microfluidics);模型, 生物学(Models, Biological);肿瘤(Neoplasms);T淋巴细胞亚群(T-Lymphocyte Subsets)

DOI 10.4049/jimmunol.2100656

PMID 35091434

发布时间 2024-09-23

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Microfluidic Squeezing Enables MHC Class I Antigen Presentation by Diverse Immune Cells to Elicit CD8<sup>+</sup> T Cell Responses with Antitumor Activity.

Journal of immunology (Baltimore, Md.

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Journal of immunology (Baltimore, Md.

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Microfluidic Squeezing Enables MHC Class I Antigen Presentation by Diverse Immune Cells to Elicit CD8<sup>+</sup> T Cell Responses with Antitumor Activity.

Journal of immunology (Baltimore, Md.

相似文献

Journal of immunology (Baltimore, Md.

相关期刊

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