Design and optimization of cranberry extract loaded bile salt augmented liposomes for targeting of MCP-1/STAT3/VEGF signaling pathway in DMN-intoxicated liver in rats.
第一作者:
Sara,M Soliman
第一单位:
Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, October 6 University, 6th of October City, Giza, 12585, Egypt.
作者:
医学主题词
动物(Animals);胆汁酸类和盐类(Bile Acids and Salts);化学, 药物(Chemistry, Pharmaceutical);二甲基亚硝胺(Dimethylnitrosamine);疾病模型, 动物(Disease Models, Animal);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物载体(Drug Carriers);炎症介导素类(Inflammation Mediators);脂质体(Liposomes);肝功能试验(Liver Function Tests);男(雄)性(Male);氧化性应激(Oxidative Stress);植物提取物(Plant Extracts);大鼠(Rats);大鼠, Wistar(Rats, Wistar);受体, CCR2(Receptors, CCR2);STAT3转录因子(STAT3 Transcription Factor);表面特性(Surface Properties);大果越橘(Vaccinium macrocarpon);血管内皮生长因子A(Vascular Endothelial Growth Factor A)
DOI
10.1080/10717544.2022.2032875
PMID
35098843
发布时间
2022-02-05
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Drug delivery
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