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首页> Oncology reports> Epigenetic therapy with chidamide alone or combined with 5‑azacitidine exerts antitumour effects on acute myeloid leukaemia cells <i>in vitro</i>.

Epigenetic therapy with chidamide alone or combined with 5‑azacitidine exerts antitumour effects on acute myeloid leukaemia cells <i>in vitro</i>.

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作者： Zheng,Li ^[1] ; Jian,Zhang ^[2] ; Min,Zhou ^[3] ; Jin-Li,Li ^[4] ; Qiao-Cheng,Qiu ^[1] ; Jian-Hong,Fu ^[1] ; Sheng-Li,Xue ^[1] ; Hui-Ying,Qiu ^[1]

作者单位： National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, P.R. China. ^[1] Department of Blood Transfusion, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, P.R. China. ^[2] Department of Hematology, Changshu Affiliated Hospital of Soochow University, The First People's Hospital of Changshu, Changshu, Jiangsu 215500, P.R. China. ^[3] State Key Laboratory of Radiation Medicine and Protection, Oncology Radiotherapy Department, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, P.R. China. ^[4]

关键词 5?azacitidine acute myeloid leukaemia apoptosis chidamide differentiation proliferation

主题词氨基吡啶类(Aminopyridines);抗代谢药, 抗肿瘤(Antimetabolites, Antineoplastic);细胞凋亡(Apoptosis);阿扎胞苷(Azacitidine);苯甲酰胺类(Benzamides);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);减量调节(Down-Regulation);药物协同作用(Drug Synergism);表观基因组学(Epigenomics);人类(Humans);白血病, 髓样, 急性(Leukemia, Myeloid, Acute);U937细胞(U937 Cells);增量调节(Up-Regulation)

DOI 10.3892/or.2022.8277

PMID 35103292

发布时间 2022-03-04

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Oncology reports

Oncology reports

2022年47卷4期

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