Global Metabolomic Profiling Reveals Disrupted Lipid and Amino Acid Metabolism Between the Acute and Chronic Stages of Ischemic Stroke.

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作者： Evgeny V,Sidorov ^[1] ; Chao,Xu ^[2] ; Jonathan,Garcia-Ramiu ^[3] ; Apple,Blair ^[3] ; Jorge,Ortiz-Garcia ^[3] ; David,Gordon ^[4] ; Juliane,Chainakul ^[3] ; Dharambir K,Sanghera ^[5]

作者单位： Department of Neurology, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma city, Oklahoma, USA; Oklahoma Center for Neuroscience, University of Oklahoma Health Sciences Center, USA. Electronic address: evgeny-sidorov@ouhsc.edu. ^[1] Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center, USA. ^[2] Department of Neurology, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma city, Oklahoma, USA. ^[3] Department of Neurology, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma city, Oklahoma, USA; Oklahoma Center for Neuroscience, University of Oklahoma Health Sciences Center, USA. ^[4] Oklahoma Center for Neuroscience, University of Oklahoma Health Sciences Center, USA; Pediatrics, College of Medicine, University of Oklahoma Health Sciences Center, USA; Harold Hamm Diabetes Center, University of Oklahoma Health Sciences Center, USA; Physiology, College of Medicine, University of Oklahoma Health Sciences Center, USA; Pharmaceutical Sciences, College of Pharmacy, University of Oklahoma Health Sciences Center, USA. ^[5]

关键词 Acute and chronic ischemic stroke Biomarkers Fatty acids Metabolomics Monoacylglycerols Sphingolipids

主题词氨基酸类(Amino Acids);人类(Humans);代谢组学(Metabolomics);试点项目(Pilot Projects);鞘脂类(Sphingolipids)

DOI 10.1016/j.jstrokecerebrovasdis.2022.106320

PMID 35104745

发布时间 2023-07-01

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