Coinfection with SARS-CoV-2 and Influenza A Virus Increases Disease Severity and Impairs Neutralizing Antibody and CD4<sup>+</sup> T Cell Responses.

导出 OA

翻译打印收藏纠错

第一作者： Eun-Ha,Kim

第一单位： College of Medicine and Medical Research Institute, Chungbuk National Universitygrid.254229.a, Cheongju, Republic of Korea.

作者： Eun-Ha,Kim ^[1] ; Thi-Quyen,Nguyen ^[2] ; Mark Anthony B,Casel ^[1] ; Rare,Rollon ^[1] ; Se-Mi,Kim ^[3] ; Young-Il,Kim ^[3] ; Kwang-Min,Yu ^[1] ; Seung-Gyu,Jang ^[4] ; Jihyun,Yang ^[5] ; Haryoung,Poo ^[5] ; Jae U,Jung ^[6] ; Young Ki,Choi ^[4]

作者单位： College of Medicine and Medical Research Institute, Chungbuk National Universitygrid.254229.a, Cheongju, Republic of Korea. ^[1] College of Medicine and Medical Research Institute, Chungbuk National Universitygrid.254229.a, Cheongju, Republic of Korea.;Vinmec Research Institute of Stem Cell and Gene Technology, Vinmec Healthcare System, Hanoi, Vietnam. ^[2] Center for Study of Emerging and Re-emerging Viruses, Korea Virus Research Institute, Institute for Basic Science (IBS), Daejeon, Republic of Korea. ^[3] College of Medicine and Medical Research Institute, Chungbuk National Universitygrid.254229.a, Cheongju, Republic of Korea.;Center for Study of Emerging and Re-emerging Viruses, Korea Virus Research Institute, Institute for Basic Science (IBS), Daejeon, Republic of Korea. ^[4] Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, University of Science and Technology, Daejeon, Republic of Korea. ^[5] Department of Cancer Biology and Global Center for Pathogens Research and Human Health, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA. ^[6]

关键词 SARS-CoV-2 T cell bronchoalveolar lavage fluid chemokine coinfection cytokine hACE2 mice immune response influenza A virus neutralizing antibody