首页> Journal of neuroinflammation> Elevated proportion of TLR2- and TLR4-expressing Th17-like cells and activated memory B cells was associated with clinical activity of cerebral cavernous malformations.

Elevated proportion of TLR2- and TLR4-expressing Th17-like cells and activated memory B cells was associated with clinical activity of cerebral cavernous malformations.

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第一作者： Camilla,Castro

第一单位： Department of Microbiology and Parasitology, Federal University of the State of Rio de Janeiro, Frei Caneca 94, Rio de Janeiro, RJ, 20261-040, Brazil.;Post-Graduate Program in Microbiology, University of the State of Rio de Janeiro, Rio de Janeiro, Brazil.

作者： Camilla,Castro ^[1] ; Hugo A A,Oyamada ^[1] ; Marcos Octávio S D,Cafasso ^[2] ; Lana M,Lopes ^[1] ; Clarice,Monteiro ^[1] ; Priscila M,Sacramento ^[1] ; Soniza Vieira,Alves-Leon ^[3] ; Gustavo,da Fontoura Galvão ^[4] ; Joana,Hygino ^[5] ; Jorge Paes Barreto Marcondes,de Souza ^[6] ; Cleonice A M,Bento ^[7]

作者单位： Department of Microbiology and Parasitology, Federal University of the State of Rio de Janeiro, Frei Caneca 94, Rio de Janeiro, RJ, 20261-040, Brazil.;Post-Graduate Program in Microbiology, University of the State of Rio de Janeiro, Rio de Janeiro, Brazil. ^[1] Department of Microbiology and Parasitology, Federal University of the State of Rio de Janeiro, Frei Caneca 94, Rio de Janeiro, RJ, 20261-040, Brazil. ^[2] Post-Graduate Program in Neurology, University of the State of Rio de Janeiro, Rio de Janeiro, Brazil.;Translational Neuroscience Laboratory (LabNet), University of the State of Rio de Janeiro, Rio de Janeiro, Brazil. ^[3] Service of Neurosurgery, University Hospital of the Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil. ^[4] Department of Microbiology and Parasitology, Federal University of the State of Rio de Janeiro, Frei Caneca 94, Rio de Janeiro, RJ, 20261-040, Brazil.;Post-Graduate Program in Neurology, University of the State of Rio de Janeiro, Rio de Janeiro, Brazil. ^[5] Post-Graduate Program in Neurology, University of the State of Rio de Janeiro, Rio de Janeiro, Brazil.;Service of Neurosurgery, University Hospital of the Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.;Post-Graduate Program of Surgical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. ^[6] Department of Microbiology and Parasitology, Federal University of the State of Rio de Janeiro, Frei Caneca 94, Rio de Janeiro, RJ, 20261-040, Brazil. cbento@unirio.br.;Post-Graduate Program in Microbiology, University of the State of Rio de Janeiro, Rio de Janeiro, Brazil. cbento@unirio.br.;Post-Graduate Program in Neurology, University of the State of Rio de Janeiro, Rio de Janeiro, Brazil. cbento@unirio.br. ^[7]

关键词 B cells Cerebral cavernous malformations Cytokines LPS T cells TLR Th17 cells

医学主题词血管瘤, 海绵状, 中枢神经系统(Hemangioma, Cavernous, Central Nervous System);人类(Humans);Th17细胞(Th17 Cells);Toll样受体2(Toll-Like Receptor 2);Toll样受体4(Toll-Like Receptor 4)

DOI 10.1186/s12974-022-02385-2

PMID 35109870

发布时间 2024-08-22

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