Combined IL-2, agonistic CD3 and 4-1BB stimulation preserve clonotype hierarchy in propagated non-small cell lung cancer tumor-infiltrating lymphocytes.

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第一作者： Parin,Shah

第一单位： Melanoma Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

作者： Parin,Shah ^[1] ; Marie-Andrée,Forget ^[1] ; Meredith L,Frank ^[2] ; Peixin,Jiang ^[3] ; Donastas,Sakellariou-Thompson ^[3] ; Lorenzo,Federico ^[2] ; Roohussaba,Khairullah ^[1] ; Chantal Alexia,Neutzler ^[3] ; Ignacio,Wistuba ^[2] ; Chi-Wan B,Chow ^[3] ; Yan,Long ^[4] ; Junya,Fujimoto ^[4] ; Shiaw-Yih,Lin ^[4] ; Anirban,Maitra ^[4] ; Marcelo V,Negrao ^[5] ; Kyle Gregory,Mitchell ^[4] ; Annikka,Weissferdt ^[3] ; Ara A,Vaporciyan ^[6] ; Tina,Cascone ^[7] ; Jack A,Roth ^[6] ; Jianjun,Zhang ^[3] ; Boris,Sepesi ^[6] ; Don L,Gibbons ^[3] ; John V,Heymach ^[6] ; Cara L,Haymaker ^[3] ; Daniel J,McGrail ^[3] ; Alexandre,Reuben ^[4] ; Chantale,Bernatchez ^[8]

作者单位： Melanoma Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA. ^[1] Biologics Development, University of Texas MD Anderson Cancer Center, Houston, Texas, USA. ^[2] Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA. ^[3] Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA. ^[4] Department of Systems Biology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA. ^[5] Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA. ^[6] Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA. ^[7] Department of Systems Biology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA cbernatchez@mdanderson.org AReuben@mdanderson.org djmcgrail@mdanderson.org. ^[8] Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA cbernatchez@mdanderson.org AReuben@mdanderson.org djmcgrail@mdanderson.org. ^[9] Melanoma Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA cbernatchez@mdanderson.org AReuben@mdanderson.org djmcgrail@mdanderson.org. ^[10]

关键词 adoptive antigen immunotherapy lung neoplasms lymphocytes receptors translational medical research tumor-infiltrating

主题词老年人(Aged);老年人, 80以上(Aged, 80 and over);癌, 非小细胞肺(Carcinoma, Non-Small-Cell Lung);女(雌)性(Female);人类(Humans);白细胞介素2(Interleukin-2);肺肿瘤(Lung Neoplasms);淋巴细胞, 肿瘤浸润(Lymphocytes, Tumor-Infiltrating);男(雄)性(Male);中年人(Middle Aged)

DOI 10.1136/jitc-2021-003082

PMID 35110355

发布时间 2022-03-23

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Journal for immunotherapy of cancer

2022年10卷2期

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Combined IL-2, agonistic CD3 and 4-1BB stimulation preserve clonotype hierarchy in propagated non-small cell lung cancer tumor-infiltrating lymphocytes.

Journal for immunotherapy of cancer

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Journal for immunotherapy of cancer

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Combined IL-2, agonistic CD3 and 4-1BB stimulation preserve clonotype hierarchy in propagated non-small cell lung cancer tumor-infiltrating lymphocytes.

Journal for immunotherapy of cancer

相似文献

Journal for immunotherapy of cancer

相关期刊

检索历史清除