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The IGFBP3/TMEM219 pathway regulates beta cell homeostasis.

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作者单位: International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, DIBIC, Università di Milano, Milan, Italy. [1] Nephrology Division, Boston Children's Hospital and Transplantation Research Center, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. [2] Enthera S.r.l., Milano, Italy. [3] Diabetology Unit, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy. [4] NEST-Scuola Normale Superiore, Pisa, Italy. [5] Transplantation Research Center, Nephrology Division, Brigham and Women's Hospital, Boston, MA, USA. [6] Medicine, Al-Azhar University, Cairo, Egypt. [7] Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy. [8] Department of Medicine, University of Tennessee, Memphis, TN, USA. [9] Section of Diabetes and Metabolic Disease, Department of Clinical and Experimental Medicine, University of Pisa and Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy. [10] Department of Medicine and Surgery, Unit of Pathology, University of Parma, Parma, Italy. [11] Department of Medicine, University of Padua, Padua, Italy. [12] General Surgery, DIBIC, L. Sacco Hospital, Università di Milano, Milan, Italy. [13] Division of Transplantation, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. [14] Diabetes Service, Endocrinology and Metabolic Diseases Unit, IRCCS Cà Granda - Ospedale Maggiore Policlinico Foundation, Milan, Italy. [15] 3rd Department of Internal Medicine, Charles University, First Faculty of Medicine, Prague, Czech Republic. [16] Clinical Islet Transplant Program, Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada. [17] Endocrinology and Metabolism, Department of Health Science, Università di Milano, ASST Santi Paolo e Carlo, Milan, Italy. [18] Crown Princess Victoria Children´s Hospital and Div of Pediatrics, Dept of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden. [19] Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, DIBIC, Università di Milano and Department of Pediatrics, Buzzi Children's Hospital, Milan, Italy. [20] International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, DIBIC, Università di Milano, Milan, Italy. paolo.fiorina@childrens.harvard.edu. [21] Nephrology Division, Boston Children's Hospital and Transplantation Research Center, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. paolo.fiorina@childrens.harvard.edu. [22] Division of Endocrinology, ASST Fatebenefratelli-Sacco, Milan, Italy. paolo.fiorina@childrens.harvard.edu. [23]
DOI 10.1038/s41467-022-28360-2
PMID 35115561
发布时间 2024-02-26
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