作者:
Michael E,Belloy [1]
;
Sarah J,Eger [2]
;
Yann,Le Guen [2]
;
Vincent,Damotte [3]
;
Shahzad,Ahmad [4]
;
M Arfan,Ikram [5]
;
Alfredo,Ramirez [6]
;
Anthoula C,Tsolaki [7]
;
Giacomina,Rossi [8]
;
Iris E,Jansen [9]
;
Itziar,de Rojas [10]
;
Kayenat,Parveen [11]
;
Kristel,Sleegers [12]
;
Martin,Ingelsson [13]
;
Mikko,Hiltunen [14]
;
Najaf,Amin [15]
;
Ole,Andreassen [16]
;
Pascual,Sánchez-Juan [17]
;
Patrick,Kehoe [18]
;
Philippe,Amouyel [3]
;
Rebecca,Sims [19]
;
Ruth,Frikke-Schmidt [20]
;
Wiesje M,van der Flier [21]
;
Jean-Charles,Lambert [3]
;
European Alzheimer & Dementia BioBank (EADB) [22]
;
Zihuai,He [23]
;
Summer S,Han [24]
;
Valerio,Napolioni [2]
;
Michael D,Greicius
作者单位:
Department of Neurology and Neurological Sciences - Greicius lab, Stanford University, 290 Jane Stanford Way, Stanford, CA, 94304, USA. mbelloy@stanford.edu.
[1]
Department of Neurology and Neurological Sciences - Greicius lab, Stanford University, 290 Jane Stanford Way, Stanford, CA, 94304, USA.
[2]
Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1167-RID-AGE Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France.
[3]
Department of Epidemiology, ErasmusMC, Rotterdam, The Netherlands.;Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.
[4]
Department of Epidemiology, ErasmusMC, Rotterdam, The Netherlands.
[5]
Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.;Department of Neurodegenerative diseases and Geriatric Psychiatry, Medical Faculty, University Hospital Bonn, Bonn, Germany.;Department of Psychiatry & Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, San Antonio, TX, USA.;German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.;Cluster of Excellence Cellular Stress Responses in Aging-associated Diseases (CECAD), University of Cologne, Cologne, Germany.
[6]
1st Department of Neurology, AHEPA Hospital, Aristotle University of Thessaloniki, Athens, Greece.
[7]
Unit of Neurology V and Neuropathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
[8]
Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.;Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije University, Amsterdam, The Netherlands.
[9]
Research Center and Memory Clinic, ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.;Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.
[10]
Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.;Department of Neurodegenerative diseases and Geriatric Psychiatry, Medical Faculty, University Hospital Bonn, Bonn, Germany.
[11]
Complex Genetics of Alzheimer's Disease Group, Center for Molecular Neurology, VIB, Antwerp, Belgium.;Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.
[12]
Department of Public Health and Carins Sciences/Geriatrics, Uppsala University, Uppsala, Sweden.
[13]
Institute of Biomedicine, University of Eastern Finland, Yliopistonranta 1E, 70211, Kuopio, Finland.
[14]
Department of Epidemiology, ErasmusMC, Rotterdam, The Netherlands.;Nuffield Department of Population Health Oxford University, Oxford, UK.
[15]
NORMENT Centre, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.;Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
[16]
CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.;Neurology Service, Marqués de Valdecilla University Hospital (University of Cantabria and IDIVAL), Santander, Spain.
[17]
Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
[18]
Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Wales, UK.
[19]
Department of Clinical Biochemistry, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.;Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
[20]
Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.
[21]
Department of Neurology and Neurological Sciences - Greicius lab, Stanford University, 290 Jane Stanford Way, Stanford, CA, 94304, USA.;Quantitative Sciences Unit, Department of Medicine, Stanford University, Stanford, CA, 94304, USA.
[22]
Quantitative Sciences Unit, Department of Medicine, Stanford University, Stanford, CA, 94304, USA.;Department of Neurosurgery, Stanford University, Stanford, CA, 94304, USA.
[23]
School of Biosciences and Veterinary Medicine, University of Camerino, 62032, Camerino, Italy.
[24]
主题词
阿尔茨海默病(Alzheimer Disease);载脂蛋白E4(Apolipoprotein E4);载脂蛋白E类(Apolipoproteins E);疾病遗传易感性(Genetic Predisposition to Disease);基因型(Genotype);人类(Humans);中年人(Middle Aged);质量控制(Quality Control)
DOI
10.1186/s13195-022-00962-4
PMID
35120553
发布时间
2024-12-11
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Alzheimer's research & therapy
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