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Challenges at the APOE locus: a robust quality control approach for accurate APOE genotyping.

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作者单位: Department of Neurology and Neurological Sciences - Greicius lab, Stanford University, 290 Jane Stanford Way, Stanford, CA, 94304, USA. mbelloy@stanford.edu. [1] Department of Neurology and Neurological Sciences - Greicius lab, Stanford University, 290 Jane Stanford Way, Stanford, CA, 94304, USA. [2] Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1167-RID-AGE Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France. [3] Department of Epidemiology, ErasmusMC, Rotterdam, The Netherlands.;Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands. [4] Department of Epidemiology, ErasmusMC, Rotterdam, The Netherlands. [5] Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.;Department of Neurodegenerative diseases and Geriatric Psychiatry, Medical Faculty, University Hospital Bonn, Bonn, Germany.;Department of Psychiatry & Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, San Antonio, TX, USA.;German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.;Cluster of Excellence Cellular Stress Responses in Aging-associated Diseases (CECAD), University of Cologne, Cologne, Germany. [6] 1st Department of Neurology, AHEPA Hospital, Aristotle University of Thessaloniki, Athens, Greece. [7] Unit of Neurology V and Neuropathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy. [8] Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.;Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije University, Amsterdam, The Netherlands. [9] Research Center and Memory Clinic, ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.;Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain. [10] Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.;Department of Neurodegenerative diseases and Geriatric Psychiatry, Medical Faculty, University Hospital Bonn, Bonn, Germany. [11] Complex Genetics of Alzheimer's Disease Group, Center for Molecular Neurology, VIB, Antwerp, Belgium.;Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium. [12] Department of Public Health and Carins Sciences/Geriatrics, Uppsala University, Uppsala, Sweden. [13] Institute of Biomedicine, University of Eastern Finland, Yliopistonranta 1E, 70211, Kuopio, Finland. [14] Department of Epidemiology, ErasmusMC, Rotterdam, The Netherlands.;Nuffield Department of Population Health Oxford University, Oxford, UK. [15] NORMENT Centre, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.;Institute of Clinical Medicine, University of Oslo, Oslo, Norway. [16] CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.;Neurology Service, Marqués de Valdecilla University Hospital (University of Cantabria and IDIVAL), Santander, Spain. [17] Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. [18] Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Wales, UK. [19] Department of Clinical Biochemistry, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.;Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark. [20] Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands. [21] Department of Neurology and Neurological Sciences - Greicius lab, Stanford University, 290 Jane Stanford Way, Stanford, CA, 94304, USA.;Quantitative Sciences Unit, Department of Medicine, Stanford University, Stanford, CA, 94304, USA. [22] Quantitative Sciences Unit, Department of Medicine, Stanford University, Stanford, CA, 94304, USA.;Department of Neurosurgery, Stanford University, Stanford, CA, 94304, USA. [23] School of Biosciences and Veterinary Medicine, University of Camerino, 62032, Camerino, Italy. [24]
DOI 10.1186/s13195-022-00962-4
PMID 35120553
发布时间 2024-12-11
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