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首页> Carbohydrate polymers> Polyaminated pullulan, a new biodegradable and cationic pullulan derivative for mucosal drug delivery.

Polyaminated pullulan, a new biodegradable and cationic pullulan derivative for mucosal drug delivery.

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作者： Nguyet-Minh Nguyen,Le ^[1] ; Bao,Le-Vinh ^[1] ; Julian David,Friedl ^[2] ; Aamir,Jalil ^[3] ; Gergely,Kali ^[2] ; Andreas,Bernkop-Schnürch ^[4]

作者单位： Center for Chemistry and Biomedicine, Department of Pharmaceutical Technology, Institute of Pharmacy, University of Innsbruck, Austria; Department of Industrial Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City, Viet Nam. ^[1] Center for Chemistry and Biomedicine, Department of Pharmaceutical Technology, Institute of Pharmacy, University of Innsbruck, Austria. ^[2] Center for Chemistry and Biomedicine, Department of Pharmaceutical Technology, Institute of Pharmacy, University of Innsbruck, Austria; Department of Pharmaceutics, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, Pakistan. ^[3] Center for Chemistry and Biomedicine, Department of Pharmaceutical Technology, Institute of Pharmacy, University of Innsbruck, Austria. Electronic address: andreas.bernkop@uibk.ac. ^[4]

关键词 Cationic polysaccharide Controlled drug release Mucoadhesive Non-covalent interactions Polyaminated pullulans

主题词黏着性(Adhesiveness);动物(Animals);Caco-2细胞(Caco-2 Cells);细胞存活(Cell Survival);药物释放系统(Drug Delivery Systems);乙二胺类(Ethylenediamines);葡聚糖类(Glucans);糖苷水解酶类(Glycoside Hydrolases);人类(Humans);肠黏膜(Intestinal Mucosa);黏液(Mucus);聚乙烯亚胺(Polyethyleneimine);流变学(Rheology);猪(Swine);拉伸强度(Tensile Strength);黏度(Viscosity)

DOI 10.1016/j.carbpol.2022.119143

PMID 35123754

发布时间 2022-03-30

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