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Integrating bulk and single-cell RNA sequencing reveals cellular heterogeneity and immune infiltration in hepatocellular carcinoma.

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第一作者： Tingjie,Wang

第一单位： School of Automation Science and Engineering, Faculty of Electronic and Information Engineering, Xi'an Jiaotong University, China.

作者： Tingjie,Wang ^[1] ; Ningxin,Dang ^[2] ; Guangbo,Tang ^[3] ; Zihang,Li ^[3] ; Xiujuan,Li ^[1] ; Bingyin,Shi ^[4] ; Zhong,Xu ^[5] ; Lei,Li ^[6] ; Xiaofei,Yang ^[7] ; Chuanrui,Xu ^[6] ; Kai,Ye ^[8]

作者单位： School of Automation Science and Engineering, Faculty of Electronic and Information Engineering, Xi'an Jiaotong University, China. ^[1] Genome Institute, The First Affiliated Hospital of Xi'an Jiaotong University, China. ^[2] School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, China. ^[3] Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, China. ^[4] Guizhou Provincial People's Hospital, Guiyang, China. ^[5] School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ^[6] Genome Institute, The First Affiliated Hospital of Xi'an Jiaotong University, China.;School of Computer Science and Technology, Faculty of Electronic and Information Engineering, Xi'an Jiaotong University, China. ^[7] School of Automation Science and Engineering, Faculty of Electronic and Information Engineering, Xi'an Jiaotong University, China.;Genome Institute, The First Affiliated Hospital of Xi'an Jiaotong University, China.;School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, China.;Faculty of Science, Leiden University, The Netherlands.;MOE Key Lab for Intelligent Networks & Networks Security, Faculty of Electronic and Information Engineering, Xi'an Jiaotong University, China. ^[8]

关键词 HCC multiomics single cell transcript factor tumor heterogeneity

医学主题词癌, 肝细胞(Carcinoma, Hepatocellular);人类(Humans);肝肿瘤(Liver Neoplasms);序列分析, RNA(Sequence Analysis, RNA);肿瘤微环境(Tumor Microenvironment)

DOI 10.1002/1878-0261.13190

PMID 35124891

发布时间 2023-09-16

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