Pure drug nano-assemblies: A facile carrier-free nanoplatform for efficient cancer therapy.

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作者： Shuwen,Fu ^[1] ; Guanting,Li ^[2] ; Wenli,Zang ^[3] ; Xinyu,Zhou ^[4] ; Kexin,Shi ^[5] ; Yinglei,Zhai ^[5]

作者单位： School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China. ^[1] Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China. ^[2] Department of Periodontology, School and Hospital of Stomatology, China Medical University, Liaoning Provincial Key Laboratory of Oral Disease, Shenyang 110016, China. ^[3] Bio-system Pharmacology, Graduate School of Medicine, Faculty of Medicine, Osaka University, Osaka 565-0871, Japan. ^[4] Department of Biomedical Engineering, School of Medical Device, Shenyang Pharmaceutical University, Shenyang 110016, China. ^[5]

关键词 ABC, accelerated blood clearance ACT, adoptive cell transfer ATO, atovaquone ATP, adenosine triphosphate BV, Biliverdin Ber, berberine CI, combination index CPT, camptothecin CTLs, cytotoxic T lymphocytes Cancer treatment Carrier-free Ce6, chlorine e6 Combination therapy DBNP, DOX-Ber nano-assemblies DBNP@CM, DBNP were cloaked with 4T1 cell membranes DCs, dendritic cells DOX, doxorubicin DPDNAs, dual pure drug nano-assemblies EGFR, epithelial growth factor receptor EPI, epirubicin EPR, enhanced permeability and retention FRET, Forster Resonance Energy Transfer GEF, gefitinib HCPT, hydroxycamptothecin HMGB1, high-mobility group box 1 IC50, half maximal inhibitory concentration ICB, immunologic checkpoint blockade ICD, immunogenic cell death ICG, indocyanine green ITM, immunosuppressive tumor microenvironment MDS, molecular dynamics simulations MPDNAs, multiple pure drug nano-assemblies MRI, magnetic resonance imaging MTX, methotrexate NIR, near-infrared NPs, nanoparticles NSCLC, non-small cell lung cancer Nano-DDSs, nanoparticulate drug delivery systems Nanomedicine Nanotechnology PAI, photoacoustic imaging PD-1, PD receptor 1 PD-L1, PD receptor 1 ligand PDNAs, pure drug nano-assemblies PDT, photodynamic therapy PPa, pheophorbide A PTT, photothermal therapy PTX, paclitaxel Poly I:C, polyriboinosinic:polyribocytidylic acid Pure drug QSNAP, quantitative structure-nanoparticle assembly prediction RBC, red blood cell RNA, ribonucleic acid ROS, reactive oxygen species SPDNAs, single pure drug nano-assemblies Self-assembly TA, tannic acid TEM, transmission electron microscopy TLR4, Toll-like receptor 4 TME, tumor microenvironment TNBC, triple negative breast TTZ, trastuzumab Top I & II, topoisomerase I & II UA, ursolic acid YSV, tripeptide tyroservatide ZHO, Z-Histidine-Obzl dsRNA, double-stranded RNA α-PD-L1, anti-PD-L1 monoclonal antibody

DOI 10.1016/j.apsb.2021.08.012

PMID 35127374

发布时间 2023-11-05

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Acta pharmaceutica Sinica. B

2022年12卷1期

92-106页

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Pure drug nano-assemblies: A facile carrier-free nanoplatform for efficient cancer therapy.

Acta pharmaceutica Sinica. B

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Acta pharmaceutica Sinica. B

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Pure drug nano-assemblies: A facile carrier-free nanoplatform for efficient cancer therapy.

Acta pharmaceutica Sinica. B

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Acta pharmaceutica Sinica. B

相关期刊

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