Targeting the Inflammasome in Cardiovascular Disease.

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作者： Maria Belland,Olsen ^[1] ; Ida,Gregersen ^[1] ; Øystein,Sandanger ^[2] ; Kuan,Yang ^[1] ; Marina,Sokolova ^[3] ; Bente E,Halvorsen ^[4] ; Lars,Gullestad ^[5] ; Kaspar,Broch ^[6] ; Pål,Aukrust ^[7] ; Mieke C,Louwe ^[1]

作者单位： Research Institute of Internal Medicine, Oslo University Hospital, Oslo, Norway. ^[1] Research Institute of Internal Medicine, Oslo University Hospital, Oslo, Norway.;Section of Dermatology, Oslo University Hospital Rikshospitalet, Oslo, Norway. ^[2] Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Norway.;Department of Immunology, Oslo University Hospital, Oslo, Norway. ^[3] Research Institute of Internal Medicine, Oslo University Hospital, Oslo, Norway.;Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Norway. ^[4] Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Norway.;Department of Cardiology, Oslo University Hospital, Rikshospitalet, Oslo, Norway.;K.G. Jebsen Cardiac Research Center, Center for Heart Failure Research, Faculty of Medicine, University of Oslo, Oslo, Norway. ^[5] Department of Cardiology, Oslo University Hospital, Rikshospitalet, Oslo, Norway.;K.G. Jebsen Cardiac Research Center, Center for Heart Failure Research, Faculty of Medicine, University of Oslo, Oslo, Norway. ^[6] Research Institute of Internal Medicine, Oslo University Hospital, Oslo, Norway.;Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Norway.;Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital Rikshospitalet, Oslo, Norway. ^[7]

关键词 ACS, acute coronary syndrome AIM2, absent in melanoma 2 ASC, apoptosis associated speck-like protein ATP, adenosine triphosphate CAD, coronary artery disease CRP, C-reactive protein CVD, cardiovascular disease DAMP, damage associated molecular pattern GSDMD, gasdermin-D GSDMD-NT, gasdermin-D N-terminal HF, heart failure HFpEF, HF with preserved ejection fraction HFrEF, HF with reduced ejection fraction IL, interleukin IL-1 LDL, low-density lipoprotein LV, left ventricular LVEF, left ventricular ejection fraction MI, myocardial infarction NF-κB, nuclear factor κB NLR, NOD-like receptor NLRP3 NLRP3, NOD-like receptor family pyrin domain containing 3 NOD, nucleotide-binding oligomerization domain PRR, pattern recognition receptor STEMI, ST-elevation myocardial infarction TLR, toll-like receptor atherosclerosis cardiovascular disease heart failure inflammasome

DOI 10.1016/j.jacbts.2021.08.006

PMID 35128212

发布时间 2024-08-22

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JACC. Basic to translational science

2022年7卷1期

84-98页

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Targeting the Inflammasome in Cardiovascular Disease.

JACC. Basic to translational science

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JACC. Basic to translational science

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Targeting the Inflammasome in Cardiovascular Disease.

JACC. Basic to translational science

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JACC. Basic to translational science

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