New Therapeutic Strategies Have Changed the Natural History of Pediatric Crohn's Disease: A Two-Decade Population-Based Study.

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作者： Delphine,Ley ^[1] ; Ariane,Leroyer ^[2] ; Claire,Dupont ^[3] ; Hélène,Sarter ^[2] ; Valérie,Bertrand ^[4] ; Claire,Spyckerelle ^[5] ; Nathalie,Guillon ^[6] ; Pauline,Wils ^[7] ; Guillaume,Savoye ^[8] ; Dominique,Turck ^[9] ; Corinne,Gower-Rousseau ^[10] ; Mathurin,Fumery ^[11] ; Epimad Group

作者单位： Centre Hospitalier et Universitaire Lille, Division of Gastroenterology, Hepatology, and Nutrition, Department of Paediatrics, Lille, France; Univ. Lille, Inserm, Centre Hospitalier et Universitaire Lille, U1286 INFINITE-Institute for Translational Research in Inflammation, Lille, France. Electronic address: delphine.ley@chu-lille.fr. ^[1] Univ. Lille, Inserm, Centre Hospitalier et Universitaire Lille, U1286 INFINITE-Institute for Translational Research in Inflammation, Lille, France; Centre Hospitalier et Universitaire Lille, Public Health, Epidemiology and Economic Health Unit, Epimad Registry, Maison Régionale de la Recherche Clinique, Lille, France. ^[2] Department of Paediatrics, Caen University Hospital, Caen, France. ^[3] Department of Paediatrics, Le Havre Hospital, Le Havre, France. ^[4] Department of Paediatrics, St Vincent de Paul Hospital, Lille Catholic University, Lille, France. ^[5] Centre Hospitalier et Universitaire Lille, Public Health, Epidemiology and Economic Health Unit, Epimad Registry, Maison Régionale de la Recherche Clinique, Lille, France. ^[6] Centre Hospitalier et Universitaire Lille, Gastroenterology Unit, Lille, France. ^[7] Gastroenterology Unit, Rouen University Hospital, Unité Mixte de Recherche 1073, University of Rouen Normandy, Rouen, France. ^[8] Centre Hospitalier et Universitaire Lille, Division of Gastroenterology, Hepatology, and Nutrition, Department of Paediatrics, Lille, France; Univ. Lille, Inserm, Centre Hospitalier et Universitaire Lille, U1286 INFINITE-Institute for Translational Research in Inflammation, Lille, France. ^[9] Univ. Lille, Inserm, Centre Hospitalier et Universitaire Lille, U1286 INFINITE-Institute for Translational Research in Inflammation, Lille, France; Centre Hospitalier et Universitaire Lille, Public Health, Epidemiology and Economic Health Unit, Epimad Registry, Maison Régionale de la Recherche Clinique, Lille, France; Epidemiology Unit, Robert Debré Hospital, Reims University Hospital, Reims, France. ^[10] Gastroenterology Unit, Amiens University Hospital, Peritox, Unité Mixte de Recherche I01, Université de Picardie Jules Verne, Amiens, France. ^[11]

关键词 Anti-TNF Crohn’s Disease Disease Course Inflammatory Bowel Disease

主题词儿童(Child);人类(Humans);青少年(Adolescent);Crohn病(Crohn Disease);回顾性研究(Retrospective Studies);消化系统外科手术(Digestive System Surgical Procedures);免疫抑制剂(Immunosuppressive Agents)

DOI 10.1016/j.cgh.2022.01.051

PMID 35131345

发布时间 2022-11-09

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