Irreversible alteration of extracellular vesicle and cell-free messenger RNA profiles in human plasma associated with blood processing and storage.

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第一作者： Hyun Ji,Kim

第一单位： Cancer Early Detection Advanced Research Center, Knight Cancer Institute (CEDAR), Oregon Health and Science University, 2720 SW Moody Ave, KR-CEDR, Portland, OR, 97201, USA.;Department of Biomedical Engineering, Oregon Health and Science University, Portland, OR, USA.

作者： Hyun Ji,Kim ^[1] ; Matthew J,Rames ^[1] ; Samuel,Tassi Yunga ^[1] ; Randall,Armstrong ^[2] ; Mayu,Morita ^[3] ; Anh T P,Ngo ^[4] ; Owen J T,McCarty ^[4] ; Fehmi,Civitci ^[2] ; Terry K,Morgan ^[5] ; Thuy T M,Ngo ^[6]

作者单位： Cancer Early Detection Advanced Research Center, Knight Cancer Institute (CEDAR), Oregon Health and Science University, 2720 SW Moody Ave, KR-CEDR, Portland, OR, 97201, USA.;Department of Biomedical Engineering, Oregon Health and Science University, Portland, OR, USA. ^[1] Cancer Early Detection Advanced Research Center, Knight Cancer Institute (CEDAR), Oregon Health and Science University, 2720 SW Moody Ave, KR-CEDR, Portland, OR, 97201, USA. ^[2] Department of Pathology, Oregon Health and Science University, Portland, OR, USA. ^[3] Department of Biomedical Engineering, Oregon Health and Science University, Portland, OR, USA. ^[4] Cancer Early Detection Advanced Research Center, Knight Cancer Institute (CEDAR), Oregon Health and Science University, 2720 SW Moody Ave, KR-CEDR, Portland, OR, 97201, USA.;Department of Biomedical Engineering, Oregon Health and Science University, Portland, OR, USA.;Department of Pathology, Oregon Health and Science University, Portland, OR, USA. ^[5] Cancer Early Detection Advanced Research Center, Knight Cancer Institute (CEDAR), Oregon Health and Science University, 2720 SW Moody Ave, KR-CEDR, Portland, OR, 97201, USA. ngth@ohsu.edu.;Department of Biomedical Engineering, Oregon Health and Science University, Portland, OR, USA. ngth@ohsu.edu.;Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, OR, USA. ngth@ohsu.edu. ^[6]

主题词血液(Blood);低温保存(Cryopreservation);流式细胞术(Flow Cytometry);人类(Humans);RNA, 信使(RNA, Messenger)

DOI 10.1038/s41598-022-06088-9

PMID 35136102

发布时间 2024-08-22

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