Delineating the activation mechanism and conformational landscape of a class B G protein-coupled receptor glucagon receptor.

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作者： Ying,Wang ^[1] ; Mingyu,Li ^[2] ; Wenqi,Liang ^[1] ; Xinchao,Shi ^[3] ; Jigang,Fan ^[1] ; Ren,Kong ^[1] ; Yaqin,Liu ^[4] ; Jian,Zhang ^[2] ; Ting,Chen ^[1] ; Shaoyong,Lu ^[2]

作者单位： Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University, School of Medicine, Shanghai 200025, China. ^[1] Medicinal Chemistry and Bioinformatics Center, Shanghai Jiao Tong University, School of Medicine, Shanghai 200025, China. ^[2] Department of Emergency, Changhai Hospital, Naval Medical University, Shanghai 200433, China. ^[3] Institute of Bioinformatics and Medical Engineering, School of Electrical and Information Engineering, Jiangsu University of Technology, Changzhou 213001, China. ^[4] Department of Cardiology, Changzheng Hospital, Naval Medical University, Shanghai 200023, China. ^[5]

关键词 Allosteric modulator GPCR Markov state model Molecular dynamics simulations

DOI 10.1016/j.csbj.2022.01.015

PMID 35140883

发布时间 2024-04-05

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Computational and structural biotechnology journal

2022年20卷

628-639页

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Delineating the activation mechanism and conformational landscape of a class B G protein-coupled receptor glucagon receptor.

Computational and structural biotechnology journal

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Computational and structural biotechnology journal

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Delineating the activation mechanism and conformational landscape of a class B G protein-coupled receptor glucagon receptor.

Computational and structural biotechnology journal

相似文献

Computational and structural biotechnology journal

相关期刊

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