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Neuropathological lesions and their contribution to dementia and cognitive impairment in a heterogeneous clinical population.

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第一作者： Dana,Godrich

第一单位： Dr. John T MacDonald Foundation Department of Human Genetics, Miller School of Medicine, University of Miami, Miami, Florida, USA.

作者： Dana,Godrich ^[1] ; Eden R,Martin ^[2] ; Gerard,Schellenberg ^[3] ; Margaret A,Pericak-Vance ^[2] ; Michael,Cuccaro ^[2] ; William K,Scott ^[2] ; Walter,Kukull ^[4] ; Thomas,Montine ^[5] ; Gary W,Beecham ^[2]

作者单位： Dr. John T MacDonald Foundation Department of Human Genetics, Miller School of Medicine, University of Miami, Miami, Florida, USA. ^[1] Dr. John T MacDonald Foundation Department of Human Genetics, Miller School of Medicine, University of Miami, Miami, Florida, USA.;John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, USA. ^[2] Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA. ^[3] Department of Epidemiology, University of Washington, Seattle, Washington, USA. ^[4] Department of Pathology, Stanford University, Stanford, California, USA. ^[5]

关键词 Alzheimer disease Lewy bodies amyloid angiopathy cognitive decline dementia hippocampal sclerosis neuritic plaques neurofibrillary neuropathology tangles vascular dementia

医学主题词人类(Humans);神经原纤维缠结(Neurofibrillary Tangles);阿尔茨海默病(Alzheimer Disease);脑(Brain);Lewy体(Lewy Bodies);斑块, 淀粉样(Plaque, Amyloid)

DOI 10.1002/alz.12516

PMID 35142102

发布时间 2025-09-28

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