Discovery and Mechanism of Small Molecule Inhibitors Selective for the Chromatin-Binding Domains of Oncogenic UHRF1.

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作者： Wallace H,Liu ^[1] ; Robert E,Miner ^[2] ; Brittany N,Albaugh ^[1] ; Gene E,Ananiev ^[2] ; Scott A,Wildman ^[1] ; John M,Denu ^[2]

作者单位： Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States. ^[1] Wisconsin Institute for Discovery, University of Wisconsin-Madison, Madison, Wisconsin 53715, United States. ^[2] Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States. ^[3]

主题词 CCAAT增强子结合蛋白类(CCAAT-Enhancer-Binding Proteins);染色质(Chromatin);DNA甲基化(DNA Methylation);组蛋白类(Histones);人类(Humans);泛素蛋白连接酶类(Ubiquitin-Protein Ligases)

DOI 10.1021/acs.biochem.1c00698

PMID 35143176

发布时间 2023-03-02

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