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Photoreceptor Layer Thinning Is an Early Biomarker for Age-Related Macular Degeneration: Epidemiologic and Genetic Evidence from UK Biobank OCT Data.

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第一作者： Seyedeh Maryam,Zekavat

第一单位： Department of Ophthalmology and Visual Science, Yale School of Medicine, New Haven, Connecticut; Computational Biology & Bioinformatics Program, Yale University, New Haven, Connecticut; Program in Medical and Population Genetics and Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, Massachusetts; Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

作者： Seyedeh Maryam,Zekavat ^[1] ; Sayuri,Sekimitsu ^[2] ; Yixuan,Ye ^[3] ; Vineet,Raghu ^[4] ; Hongyu,Zhao ^[5] ; Tobias,Elze ^[6] ; Ayellet V,Segrè ^[6] ; Janey L,Wiggs ^[6] ; Pradeep,Natarajan ^[7] ; Lucian,Del Priore ^[8] ; Nazlee,Zebardast ^[6] ; Jay C,Wang ^[9]

作者单位： Department of Ophthalmology and Visual Science, Yale School of Medicine, New Haven, Connecticut; Computational Biology & Bioinformatics Program, Yale University, New Haven, Connecticut; Program in Medical and Population Genetics and Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, Massachusetts; Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts. ^[1] Tufts University School of Medicine, Boston, Massachusetts. ^[2] Computational Biology & Bioinformatics Program, Yale University, New Haven, Connecticut. ^[3] Program in Medical and Population Genetics and Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, Massachusetts; Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Cardiovascular Imaging Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts. ^[4] Computational Biology & Bioinformatics Program, Yale University, New Haven, Connecticut; School of Public Health, Yale University, New Haven, Connecticut. ^[5] Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts. ^[6] Program in Medical and Population Genetics and Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, Massachusetts; Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts. ^[7] Department of Ophthalmology and Visual Science, Yale School of Medicine, New Haven, Connecticut. ^[8] Department of Ophthalmology and Visual Science, Yale School of Medicine, New Haven, Connecticut; Northern California Retina Vitreous Associates, Mountain View, California. Electronic address: jay.wang@yale.edu. ^[9]