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首页> Cancer letters> Macrophages are primed to transdifferentiate into fibroblasts in malignant ascites and pleural effusions.

Macrophages are primed to transdifferentiate into fibroblasts in malignant ascites and pleural effusions.

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作者： Mamoru,Ito ^[1] ; Michitaka,Nakano ^[1] ; Hiroshi,Ariyama ^[1] ; Kyoko,Yamaguchi ^[1] ; Risa,Tanaka ^[2] ; Yuichiro,Semba ^[1] ; Takeshi,Sugio ^[1] ; Kohta,Miyawaki ^[1] ; Yoshikane,Kikushige ^[1] ; Shinichi,Mizuno ^[1] ; Taichi,Isobe ^[3] ; Kenro,Tanoue ^[1] ; Ryosuke,Taguchi ^[1] ; Shohei,Ueno ^[1] ; Takahito,Kawano ^[4] ; Masaharu,Murata ^[4] ; Eishi,Baba ^[5] ; Koichi,Akashi ^[1]

作者单位： Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan. ^[1] Department of Medical Oncology, Hamanomachi Hospital, Fukuoka, Japan. ^[2] Department of Oncology and Social Medicine, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan. ^[3] Center for Advanced Medical Innovation, Kyushu University, Fukuoka, Japan. ^[4] Department of Oncology and Social Medicine, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan. Electronic address: baba.eishi.889@m.kyushu-u.ac.jp. ^[5]

关键词 Cancer-associated fibroblast Tumor microenvironment Tumor-associated macrophage

主题词动物(Animals);腹水(Ascites);细胞黏附分子(Cell Adhesion Molecules);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);成纤维细胞(Fibroblasts);人类(Humans);巨噬细胞(Macrophages);小鼠(Mice);腹膜肿瘤(Peritoneal Neoplasms);胸腔积液(Pleural Effusion);转化生长因子β(Transforming Growth Factor beta);肿瘤微环境(Tumor Microenvironment)

DOI 10.1016/j.canlet.2022.215597

PMID 35150810

发布时间 2022-04-22

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