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首页> Experimental parasitology> Helminth antigens modulate human PBMCs, attenuating disease progression in a humanised mouse model of graft versus host disease.

Helminth antigens modulate human PBMCs, attenuating disease progression in a humanised mouse model of graft versus host disease.

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作者： Marc,Healy ^[1] ; Allison,Aldridge ^[2] ; Arlene M A,Glasgow ^[2] ; Bernard P,Mahon ^[1] ; Karen,English ^[3] ; Sandra M,O'Neill ^[4]

作者单位： Department of Biology, Maynooth University, Maynooth, County Kildare, Ireland; Kathleen Lonsdale Institute for Human Health Research, Maynooth University, Maynooth, County Kildare, Ireland. ^[1] Fundamental and Translational Immunology Group, School of Biotechnology, Faculty of Science and Health, Dublin City University, Glasnevin, Dublin 9, Ireland. ^[2] Department of Biology, Maynooth University, Maynooth, County Kildare, Ireland; Kathleen Lonsdale Institute for Human Health Research, Maynooth University, Maynooth, County Kildare, Ireland. Electronic address: karen.english@mu.ie. ^[3] Fundamental and Translational Immunology Group, School of Biotechnology, Faculty of Science and Health, Dublin City University, Glasnevin, Dublin 9, Ireland. Electronic address: sandra.oneill@dcu.ie. ^[4]

关键词 Fasciola hepatica Graft versus host disease Helminth antigens Human PBMCs Humanised mouse model

主题词动物(Animals);抗原, 蠕虫(Antigens, Helminth);疾病恶化(Disease Progression);肝片形吸虫(Fasciola hepatica);片形吸虫病(Fascioliasis);移植物抗宿主病(Graft vs Host Disease);人类(Humans);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C)

DOI 10.1016/j.exppara.2022.108231

PMID 35151653

发布时间 2022-03-14

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