首页> Cells> Characterization of Gfat1 (zeppelin) and Gfat2, Essential Paralogous Genes Which Encode the Enzymes That Catalyze the Rate-Limiting Step in the Hexosamine Biosynthetic Pathway in Drosophila melanogaster.

Characterization of Gfat1 (zeppelin) and Gfat2, Essential Paralogous Genes Which Encode the Enzymes That Catalyze the Rate-Limiting Step in the Hexosamine Biosynthetic Pathway in Drosophila melanogaster.

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第一作者： Shawn,Cotsworth

第一单位： Department of Molecular Biology and Biochemistry (MBB), Simon Fraser University, 8888 University Dr., Burnaby, BC V5A 1S6, Canada.

作者： Shawn,Cotsworth ^[1] ; Catherine J,Jackson ^[2] ; Graham,Hallson ^[1] ; Kathleen A,Fitzpatrick ^[1] ; Monika,Syrzycka ^[3] ; Alistair B,Coulthard ^[4] ; Amy,Bejsovec ^[5] ; Marcella,Marchetti ^[6] ; Sergio,Pimpinelli ^[6] ; Simon J H,Wang ^[1] ; Robert G,Camfield ^[7] ; Esther M,Verheyen ^[1] ; Donald A,Sinclair ^[1] ; Barry M,Honda ^[1] ; Arthur J,Hilliker ^[4]

作者单位： Department of Molecular Biology and Biochemistry (MBB), Simon Fraser University, 8888 University Dr., Burnaby, BC V5A 1S6, Canada. ^[1] Department of Molecular Biology and Biochemistry (MBB), Simon Fraser University, 8888 University Dr., Burnaby, BC V5A 1S6, Canada.;Department of Plastic and Reconstructive Surgery, Institute for Surgical Research, University of Oslo, N-0424 Oslo, Norway.;The Department of Medical Biochemistry, Oslo University Hospital, N-0424 Oslo, Norway.;Institute of Oral Biology, Faculty of Dentistry, University of Oslo, N-0424 Oslo, Norway. ^[2] Department of Molecular Biology and Biochemistry (MBB), Simon Fraser University, 8888 University Dr., Burnaby, BC V5A 1S6, Canada.;Allergan Canada, 500-85 Enterprise Blvd, Markham, ON L6G 0B5, Canada. ^[3] Department of Biology, York University, Toronto, ON M3J 1P3, Canada. ^[4] Department of Biology, Duke University, Durham, NC 27708, USA. ^[5] Department of Biology and Biotechnology "C. Darwin", "Sapienza" University of Rome, 00185 Rome, Italy. ^[6] BC Genome Science Centre, 675 West 10th Avenue, Vancouver, BC V5Z 1L3, Canada. ^[7]

关键词 Drosophila heterochromatin Gfat1 Gfat2 HBP hexosamine biosynthesis zeppelin

医学主题词动物(Animals);生物合成途径(Biosynthetic Pathways);黑腹果蝇(Drosophila melanogaster);常染色质(Euchromatin);谷氨酰胺(Glutamine);谷氨酰胺-果糖-6-磷酸转氨酶(异构)(Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing));己糖胺类(Hexosamines)

DOI 10.3390/cells11030448

PMID 35159258

发布时间 2024-08-22

基金项目

CIHR/Canada

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准确一般字义偏差语意偏离译文作用小提交