Upregulation of Cathepsin X in Glioblastoma: Interplay with γ-Enolase and the Effects of Selective Cathepsin X Inhibitors.

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第一作者： Bernarda,Majc

第一单位： Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, 111 Večna pot, 1000 Ljubljana, Slovenia.

作者： Bernarda,Majc ^[1] ; Anamarija,Habič ^[2] ; Metka,Novak ^[1] ; Ana,Rotter ^[2] ; Andrej,Porčnik ^[1] ; Jernej,Mlakar ^[1] ; Vera,Župunski ^[3] ; Urša,Pečar Fonović ^[4] ; Damijan,Knez ^[5] ; Nace,Zidar ^[6] ; Stanislav,Gobec ^[6] ; Janko,Kos ^[6] ; Tamara,Lah Turnšek ^[6] ; Anja,Pišlar ^[6] ; Barbara,Breznik ^[1]

作者单位： Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, 111 Večna pot, 1000 Ljubljana, Slovenia. ^[1] Jozef Stefan International Postgraduate School, 39 Jamova cesta, 1000 Ljubljana, Slovenia. ^[2] Department of Neurosurgery, University Medical Centre Ljubljana, 7 Zaloška cesta, 1000 Ljubljana, Slovenia. ^[3] Institute of Pathology, Faculty of Medicine, University of Ljubljana, 2 Korytkova ulica, 1000 Ljubljana Slovenia. ^[4] Chair of Biochemistry, Faculty of Chemistry and Chemical Technology, University of Ljubljana, 113 Večna pot, 1000 Ljubljana, Slovenia. ^[5] Faculty of Pharmacy, University of Ljubljana, 7 Aškerčeva cesta, 1000 Ljubljana, Slovenia. ^[6]

关键词 cathepsin X cathepsin X inhibitors glioblastoma glioblastoma stem cells tumor microenvironment γ-enolase