Synthesis, Biological Evaluation and Molecular Docking Studies of 5-Indolylmethylen-4-oxo-2-thioxothiazolidine Derivatives.

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作者： Volodymyr,Horishny ^[1] ; Athina,Geronikaki ^[2] ; Victor,Kartsev ^[3] ; Vasyl,Matiychuk ^[4] ; Anthi,Petrou ^[2] ; Pavel,Pogodin ^[5] ; Vladimir,Poroikov ^[5] ; Theodora A,Papadopoulou ^[6] ; Ioannis S,Vizirianakis ^[6] ; Marina,Kostic ^[7] ; Marija,Ivanov ^[8] ; Marina,Sokovic ^[8]

作者单位： Department of Chemistry, Danylo Halytsky Lviv National Medical University, Pekarska 69, 79010 Lviv, Ukraine. ^[1] Department of Pharmaceutical Chemistry, School of Pharmacy, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece. ^[2] InterBioScreen, Chernogolovka, 142432 Moscow Region, Russia. ^[3] Department of Chemistry, Ivan Franko National University of Lviv, Kyryla i Mefodia 6, 79005 Lviv, Ukraine. ^[4] Institute of Biomedical Chemistry, Pogodinskaya Street 10 Bldg.8, 119121 Moscow, Russia. ^[5] Department of Pharmacology, School of Pharmacy, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece. ^[6] Department of Life and Health Sciences, University of Nicosia, Nicosia CY-1700, Cyprus. ^[7] Mycological Laboratory, Department of Plant Physiology, Institute for Biological Research, Siniša, Stankovic-National Institute of Republic of Serbia, University of Belgrade, Bulevar Despota Stefana 142, 11000 Belgrade, Serbia. ^[8]

关键词 4-oxo-2-thioxothiazolidine CYP51 MurB antibacterial antifungal biological activity prediction docking microdilution method