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HIV-1 provirus transcription and translation in macrophages differs from pre-integrated cDNA complexes and requires E2F transcriptional programs.

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第一作者： Albebson L,Lim

第一单位： Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah, USA.;Marine Science Institute, University of the Philippines Diliman, Quezon City, Philippines.

作者： Albebson L,Lim ^[1] ; Philip,Moos ^[2] ; Christopher D,Pond ^[2] ; Erica C,Larson ^[3] ; Laura J,Martins ^[4] ; Matthew A,Szaniawski ^[4] ; Vicente,Planelles ^[4] ; Louis R,Barrows ^[2]

作者单位： Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah, USA.;Marine Science Institute, University of the Philippines Diliman, Quezon City, Philippines. ^[1] Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah, USA. ^[2] Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah, USA.;Department of Microbiology & Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. ^[3] Department of Pathology, University of Utah, Salt Lake City, Utah, USA. ^[4]

关键词 HIV-1 infection macrophages pre-integrated cDNA complex transcription provirus transcription single cell RNA sequencing

医学主题词 DNA, 互补(DNA, Complementary);HIV感染(HIV Infections);HIV-1(HIV-1);人类(Humans);巨噬细胞(Macrophages);原病毒(Proviruses)

DOI 10.1080/21505594.2022.2031583

PMID 35166645

发布时间 2024-12-14

基金项目

R01 AI143567/AI/NIAID NIH HHS/United States R21 AI124823/AI/NIAID NIH HHS/United States U01 TW008163/TW/FIC NIH HHS/United States

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