Asprosin induces vascular endothelial-to-mesenchymal transition in diabetic lower extremity peripheral artery disease.

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作者： Mei,You ^[1] ; Yushuang,Liu ^[1] ; Bowen,Wang ^[1] ; Li,Li ^[1] ; Hexuan,Zhang ^[1] ; Hongbo,He ^[1] ; Qing,Zhou ^[1] ; Tingbing,Cao ^[1] ; Lijuan,Wang ^[1] ; Zhigang,Zhao ^[1] ; Zhiming,Zhu ^[2] ; Peng,Gao ^[3] ; Zhencheng,Yan ^[4]

作者单位： Department of Hypertension and Endocrinology, Center for Hypertension and Metabolic Diseases, Daping Hospital, Army Medical University, Chongqing Institute of Hypertension, 10 Chang Jiang Zhi Lu, Yuzhong District, Chongqing, 400042, China. ^[1] Department of Hypertension and Endocrinology, Center for Hypertension and Metabolic Diseases, Daping Hospital, Army Medical University, Chongqing Institute of Hypertension, 10 Chang Jiang Zhi Lu, Yuzhong District, Chongqing, 400042, China. zhuzm@yahoo.com. ^[2] Department of Hypertension and Endocrinology, Center for Hypertension and Metabolic Diseases, Daping Hospital, Army Medical University, Chongqing Institute of Hypertension, 10 Chang Jiang Zhi Lu, Yuzhong District, Chongqing, 400042, China. gaopengscu@aliyun.com. ^[3] Department of Hypertension and Endocrinology, Center for Hypertension and Metabolic Diseases, Daping Hospital, Army Medical University, Chongqing Institute of Hypertension, 10 Chang Jiang Zhi Lu, Yuzhong District, Chongqing, 400042, China. zhenchengyan@sina.com. ^[4]

关键词 Asprosin Endothelial-to-mesenchymal transition Lower extremity peripheral artery disease TGF-β signaling pathway Type 2 diabetes mellitus

主题词动物(Animals);糖尿病, 2型(Diabetes Mellitus, Type 2);内皮, 血管(Endothelium, Vascular);人类(Humans);下肢(Lower Extremity);小鼠(Mice);外周动脉疾病(Peripheral Arterial Disease)

DOI 10.1186/s12933-022-01457-0

PMID 35168605

发布时间 2022-03-02

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