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Revealing the transcriptional heterogeneity of organ-specific metastasis in human gastric cancer using single-cell RNA Sequencing.

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第一作者： Haiping,Jiang

第一单位： Department of Medical Oncology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

作者： Haiping,Jiang ^[1] ; Dingyi,Yu ^[2] ; Penghui,Yang ^[2] ; Rongfang,Guo ^[2] ; Mei,Kong ^[3] ; Yuan,Gao ^[4] ; Xiongfei,Yu ^[5] ; Xiaoyan,Lu ^[6] ; Xiaohui,Fan ^[7]

作者单位： Department of Medical Oncology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. ^[1] Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China. ^[2] Department of Pathology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. ^[3] Department of Gastro-Intestinal Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. ^[4] Department of Surgical Oncology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. ^[5] Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.;State Key Laboratory of Component-Based Chinese Medicine, Innovation Center in Zhejiang University, Hangzhou, China. ^[6] Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.;State Key Laboratory of Component-Based Chinese Medicine, Innovation Center in Zhejiang University, Hangzhou, China.;Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China. ^[7]

关键词 HLA-E-KLRC1/KLRC2 gastric cancer metastasis single-cell RNA sequencing tumoural heterogeneity

主题词遗传异质性(Genetic Heterogeneity);人类(Humans);肿瘤转移(Neoplasm Metastasis);序列分析, RNA(Sequence Analysis, RNA);单细胞分析(Single-Cell Analysis);胃肿瘤(Stomach Neoplasms);肿瘤微环境(Tumor Microenvironment)

DOI 10.1002/ctm2.730

PMID 35184420

发布时间 2024-08-24

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