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The SWI/SNF subunit BRG1 affects alternative splicing by changing RNA binding factor interactions with nascent RNA.

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第一作者： Antoni,Gañez-Zapater

第一单位： Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, The Arrhenius Laboratories F4, 106 91, Stockholm, Sweden.;Center for Genomic Regulation, 08003, Barcelona, Spain.

作者： Antoni,Gañez-Zapater ^[1] ; Sebastian D,Mackowiak ^[2] ; Yuan,Guo ^[3] ; Marcel,Tarbier ^[4] ; Antonio,Jordán-Pla ^[5] ; Marc R,Friedländer ^[4] ; Neus,Visa ^[3] ; Ann-Kristin,Östlund Farrants ^[6]

作者单位： Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, The Arrhenius Laboratories F4, 106 91, Stockholm, Sweden.;Center for Genomic Regulation, 08003, Barcelona, Spain. ^[1] Science for Life Laboratory, Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, 106 91, Stockholm, Sweden.;Max Planck Institute for Molecular Genetics, Ihnestraße 63-73, 14195, Berlin, Germany. ^[2] Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, The Arrhenius Laboratories F4, 106 91, Stockholm, Sweden. ^[3] Science for Life Laboratory, Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, 106 91, Stockholm, Sweden. ^[4] Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, The Arrhenius Laboratories F4, 106 91, Stockholm, Sweden.;Departamento de Bioquímica y Biología Molecular, Facultad de Ciencies Biológicas, Valencia University, C/Dr. Moliner, 50, 46100, Burjassot, Spain. ^[5] Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, The Arrhenius Laboratories F4, 106 91, Stockholm, Sweden. anki.ostlund@su.se. ^[6]

关键词 BRGG1 Chromatin remodelling Exon GC content SAM68 SWI/SNF hnRNPL hnRNPU mRNA alternative splicing