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miR-98-5p as a novel biomarker suppress liver fibrosis by targeting TGFβ receptor 1.

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第一作者： Yanhua,Ma

第一单位： Peking University Ditan Teaching Hospital, Peking University Health Science Center, Beijing, China.;Center of Liver Diseases Division 3, Beijing Ditan Hospital, Capital Medical University, Peking University Ditan Teaching Hospital, 8 East Jingshun Street, Beijing, 100015, China.;Department of Infectious Diseases, Binzhou Medical University Hospital, Binzhou, Shandong, China.

作者： Yanhua,Ma ^[1] ; Xiaoxue,Yuan ^[2] ; Ming,Han ^[2] ; Yifan,Xu ^[3] ; Kai,Han ^[2] ; Pu,Liang ^[2] ; Shunai,Liu ^[2] ; Jun,Chen ^[4] ; Huichun,Xing ^[5]

作者单位： Peking University Ditan Teaching Hospital, Peking University Health Science Center, Beijing, China.;Center of Liver Diseases Division 3, Beijing Ditan Hospital, Capital Medical University, Peking University Ditan Teaching Hospital, 8 East Jingshun Street, Beijing, 100015, China.;Department of Infectious Diseases, Binzhou Medical University Hospital, Binzhou, Shandong, China. ^[1] Beijing Key Laboratory of Emerging Infectious Diseases, Beijing, China.;Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing Key Laboratory of Emerging Infectious Diseases, 8 East Jingshun Street, Beijing, 100015, China. ^[2] Peking University Ditan Teaching Hospital, Peking University Health Science Center, Beijing, China.;Center of Liver Diseases Division 3, Beijing Ditan Hospital, Capital Medical University, Peking University Ditan Teaching Hospital, 8 East Jingshun Street, Beijing, 100015, China. ^[3] Peking University Ditan Teaching Hospital, Peking University Health Science Center, Beijing, China. chengj0817@sina.cn.;Beijing Key Laboratory of Emerging Infectious Diseases, Beijing, China. chengj0817@sina.cn.;Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing Key Laboratory of Emerging Infectious Diseases, 8 East Jingshun Street, Beijing, 100015, China. chengj0817@sina.cn. ^[4] Peking University Ditan Teaching Hospital, Peking University Health Science Center, Beijing, China. hchxing@sohu.com.;Center of Liver Diseases Division 3, Beijing Ditan Hospital, Capital Medical University, Peking University Ditan Teaching Hospital, 8 East Jingshun Street, Beijing, 100015, China. hchxing@sohu.com. ^[5]

关键词 Bioinformatic analysis Biomarker Differential expression HBV infection Liver fibrosis Signaling pathway TGFβR1 Target genes miR-98-5p miRNAs

主题词病例对照研究(Case-Control Studies);基因表达谱(Gene Expression Profiling);人类(Humans);肝硬化(Liver Cirrhosis);微RNAs(MicroRNAs);信号传导(Signal Transduction)

DOI 10.1007/s12072-021-10277-5

PMID 35188624

发布时间 2025-09-30

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