Discovery of Novel Indazoles as Potent and Selective PI3Kδ Inhibitors with High Efficacy for Treatment of Hepatocellular Carcinoma.

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作者： Jifeng,Qi ^[1] ; Weihua,Wang ^[2] ; Yongmei,Tang ^[1] ; Shengying,Lou ^[1] ; Jiaer,Wang ^[2] ; Tao,Yuan ^[2] ; Qiaojun,He ^[2] ; Bo,Yang ^[2] ; Hong,Zhu ^[2] ; Sunliang,Cui ^[1]

作者单位： Institute of Drug Discovery and Design, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China. ^[1] Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China. ^[2]

主题词癌, 肝细胞(Carcinoma, Hepatocellular);I类磷脂酰肌醇3-激酶类(Class I Phosphatidylinositol 3-Kinases);人类(Humans);吲唑类(Indazoles);肝肿瘤(Liver Neoplasms);蛋白激酶抑制剂(Protein Kinase Inhibitors)

DOI 10.1021/acs.jmedchem.1c01520

PMID 35191698

发布时间 2022-05-06

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