首页> Molecular oncology> Nintedanib overcomes drug resistance from upregulation of FGFR signalling and imatinib-induced KIT mutations in gastrointestinal stromal tumours.

Nintedanib overcomes drug resistance from upregulation of FGFR signalling and imatinib-induced KIT mutations in gastrointestinal stromal tumours.

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第一作者： Juan,Liu

第一单位： Anhui Province Key Laboratory of Medical Physics and Technology, CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, China.;University of Science and Technology of China, Hefei, China.;Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, China.

作者： Juan,Liu ^[1] ; Jingjing,Gao ^[2] ; Aoli,Wang ^[3] ; Zongru,Jiang ^[3] ; Shuang,Qi ^[3] ; Ziping,Qi ^[3] ; Feiyang,Liu ^[3] ; Kailin,Yu ^[4] ; Jiangyan,Cao ^[2] ; Cheng,Chen ^[4] ; Chen,Hu ^[3] ; Hong,Wu ^[3] ; Li,Wang ^[3] ; Wenchao,Wang ^[3] ; Qingsong,Liu ^[5] ; Jing,Liu ^[3]

作者单位： Anhui Province Key Laboratory of Medical Physics and Technology, CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, China.;University of Science and Technology of China, Hefei, China.;Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, China. ^[1] Anhui Province Key Laboratory of Medical Physics and Technology, CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, China.;University of Science and Technology of China, Hefei, China. ^[2] Anhui Province Key Laboratory of Medical Physics and Technology, CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, China.;Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, China. ^[3] Anhui Province Key Laboratory of Medical Physics and Technology, CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, China. ^[4] Anhui Province Key Laboratory of Medical Physics and Technology, CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, China.;University of Science and Technology of China, Hefei, China.;Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, China.;Precision Medicine Research Laboratory of Anhui Province, Hefei, China. ^[5]

关键词 FGFR GISTs KIT imatinib resistance nintedanib