换一批
换一批Induction of Liver Size Reduction in Zebrafish Larvae by the Emerging Synthetic Cannabinoid 4F-MDMB-BINACA and Its Impact on Drug Metabolism.
第一作者：
Yu Mi,Park
第一单位：
Helmholtz Centre for Infection Research, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Campus E8 1, Saarland University, 66123 Saarbrücken, Germany.;Environmental Safety Group, Korea Institute of Science and Technology (KIST) Europe, 66123 Saarbrücken, Germany.;Department of Pharmacy, Saarland University, 66123 Saarbrücken, Germany.
作者：
关键词
cannabinoid receptors (CB1 and CB2)drug metabolismhepatotoxicitymass spectrometry imaging (MSI)methyl 2-(1-(5-fluoropentyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxamido)-3,3-dimethylbutanoate (7′N-5F-ADB)methyl 2-[1-(4-fluorobutyl)-1H-indazole-3-carboxamido]-3,3-dimethylbutanoate (4F-MDMB-BINACA)microinjectionmorpholino oligonucleotidessynthetic cannabinoid (SC)zebrafish larvae model
主题词
动物(Animals);大麻酚类(Cannabinoids);化学现象(Chemical Phenomena);幼虫(Larva);肝(Liver);代谢网络和途径(Metabolic Networks and Pathways);分子结构(Molecular Structure);器官测量(Organ Size);受体, 大麻酚(Receptors, Cannabinoid);光谱法, 质量, 基质辅助激光解吸电离(Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization);斑马鱼(Zebrafish)
DOI
10.3390/molecules27041290
PMID
35209079
发布时间
2022-03-01
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