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Impact of immune-related adverse events on the therapeutic efficacy of pembrolizumab in urothelial carcinoma: a multicenter retrospective study using time-dependent analysis.

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第一作者： Taketo,Kawai

第一单位： Department of Urology, The University of Tokyo, Tokyo, Japan.

作者： Taketo,Kawai ^[1] ; Satoru,Taguchi ^[2] ; Tohru,Nakagawa ^[3] ; Jun,Kamei ^[4] ; Yu,Nakamura ^[5] ; Daisuke,Obinata ^[6] ; Kenya,Yamaguchi ^[6] ; Tomoyuki,Kaneko ^[3] ; Shigenori,Kakutani ^[7] ; Mayuko,Tokunaga ^[8] ; Yukari,Uemura ^[9] ; Yusuke,Sato ^[1] ; Yutaka,Enomoto ^[7] ; Hiroaki,Nishimatsu ^[8] ; Tetsuya,Fujimura ^[4] ; Hiroshi,Fukuhara ^[5] ; Satoru,Takahashi ^[6] ; Haruki,Kume ^[1]

作者单位： Department of Urology, The University of Tokyo, Tokyo, Japan. ^[1] Department of Urology, The University of Tokyo, Tokyo, Japan satorutaguchi33@gmail.com.;Department of Urology, Kyorin University School of Medicine, Tokyo, Japan. ^[2] Department of Urology, Teikyo University School of Medicine, Tokyo, Japan. ^[3] Department of Urology, Jichi Medical University, Shimotsuke, Japan. ^[4] Department of Urology, Kyorin University School of Medicine, Tokyo, Japan. ^[5] Department of Urology, Nihon University School of Medicine, Tokyo, Japan. ^[6] Division of Urology, Mitsui Memorial Hospital, Tokyo, Japan. ^[7] Department of Urology, The Fraternity Memorial Hospital, Tokyo, Japan. ^[8] Department of Data Science, National Center for Global Health and Medicine, Tokyo, Japan. ^[9]

关键词 immunotherapy tumor biomarkers urinary bladder neoplasms urologic neoplasms

医学主题词老年人(Aged);女(雌)性(Female);人类(Humans);男(雄)性(Male);预后(Prognosis);回顾性研究(Retrospective Studies);膀胱肿瘤(Urinary Bladder Neoplasms)

DOI 10.1136/jitc-2021-003965

PMID 35210308

发布时间 2022-03-28

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