Mitochondrial COA7 is a heme-binding protein with disulfide reductase activity, which acts in the early stages of complex IV assembly.

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作者： Luke E,Formosa ^[1] ; Shadi,Maghool ^[2] ; Alice J,Sharpe ^[1] ; Boris,Reljic ^[1] ; Linden,Muellner-Wong ^[3] ; David A,Stroud ^[1] ; Michael T,Ryan ^[3] ; Megan J,Maher ^[3]

作者单位： Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia. ^[1] School of Chemistry and The Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC 3010, Australia. ^[2] Department of Biochemistry and Pharmacology and The Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC 3010, Australia. ^[3] Murdoch Childrens Research Institute, The Royal Children's Hospital, Parkville, VIC 3052 Australia. ^[4] Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia; michael.ryan@monash.edu megan.maher@unimelb.edu.au. ^[5] School of Chemistry and The Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC 3010, Australia; michael.ryan@monash.edu megan.maher@unimelb.edu.au. ^[6] Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC 3086, Australia. ^[7]

关键词 COA7 X-ray crystallography cytochrome c oxidase heme mitochondria