Deleting ORF71L of infectious spleen and kidney necrosis virus (ISKNV) resulted in virulence attenuation in Mandarin ﬁsh.

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作者： Hetong,Zhang ^[1] ; Hemei,Qi ^[2] ; Shaoping,Weng ^[1] ; Jianguo,He ^[3] ; Chuanfu,Dong ^[4]

作者单位： State Key Laboratory of Biocontrol/School of Life Sciences, Sun Yat-sen University, Guangzhou, 510275, China; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, 519000, China; Institute of Aquatic Economic Animals and Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-sen University, Guangzhou, 510275, China. ^[1] State Key Laboratory of Biocontrol/School of Life Sciences, Sun Yat-sen University, Guangzhou, 510275, China; Institute of Aquatic Economic Animals and Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-sen University, Guangzhou, 510275, China. ^[2] State Key Laboratory of Biocontrol/School of Life Sciences, Sun Yat-sen University, Guangzhou, 510275, China; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, 519000, China; Institute of Aquatic Economic Animals and Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-sen University, Guangzhou, 510275, China. Electronic address: lsshjg@mail.sysu.edu.cn. ^[3] State Key Laboratory of Biocontrol/School of Life Sciences, Sun Yat-sen University, Guangzhou, 510275, China; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, 519000, China; Institute of Aquatic Economic Animals and Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-sen University, Guangzhou, 510275, China. Electronic address: dongchfu@mail.sysu.edu.cn. ^[4]

关键词 ISKNV Mandarin fish Megalocytivirus Recombination Virulence