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Micropeptide PACMP inhibition elicits synthetic lethal effects by decreasing CtIP and poly(ADP-ribosyl)ation.

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第一作者: Chuanchao,Zhang
第一单位: CAS Key Laboratory of Genomics and Precision Medicine, Beijing Institute of Genomics, University of Chinese Academy of Sciences, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing 100101, China.
作者: Chuanchao,Zhang [1] ; Bo,Zhou [2] ; Feng,Gu [3] ; Hongmei,Liu [4] ; Honglin,Wu [5] ; Fuwen,Yao [1] ; Hui,Zheng [1] ; Hui,Fu [1] ; Wei,Chong [3] ; Shurui,Cai [6] ; Min,Huang [1] ; Xiaolu,Ma [1] ; Zhifang,Guo [3] ; Tingting,Li [4] ; Wenyuan,Deng [1] ; Meiwen,Zheng [1] ; Qiao,Ji [1] ; Yongliang,Zhao [1] ; Yongjie,Ma [3] ; Qi-En,Wang [6] ; Tie-Shan,Tang [7] ; Caixia,Guo [8]
作者单位: CAS Key Laboratory of Genomics and Precision Medicine, Beijing Institute of Genomics, University of Chinese Academy of Sciences, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing 100101, China. [1] CAS Key Laboratory of Genomics and Precision Medicine, Beijing Institute of Genomics, University of Chinese Academy of Sciences, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing 100101, China. Electronic address: zhoub@big.ac.cn. [2] Department of Breast Cancer Pathology and Research Laboratory, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China. [3] State Key Laboratory of Membrane Biology, Institute of Zoology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100101, China; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China. [4] CAS Key Laboratory of Genomics and Precision Medicine, Beijing Institute of Genomics, University of Chinese Academy of Sciences, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing 100101, China; State Key Laboratory of Membrane Biology, Institute of Zoology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100101, China. [5] Department of Radiation Oncology, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43016, USA. [6] State Key Laboratory of Membrane Biology, Institute of Zoology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100101, China; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China. Electronic address: tangtsh@ioz.ac.cn. [7] CAS Key Laboratory of Genomics and Precision Medicine, Beijing Institute of Genomics, University of Chinese Academy of Sciences, Chinese Academy of Sciences, China National Center for Bioinformation, Beijing 100101, China. Electronic address: guocx@big.ac.cn. [8]
DOI 10.1016/j.molcel.2022.01.020
PMID 35219381
发布时间 2022-06-06
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