Inhibiting microRNA-142-5p improves learning and memory in Alzheimer's disease rats via targeted regulation of the PTPN1-mediated Akt pathway.

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作者： Weiwei,Liang ^[1] ; Zhuojun,Xie ^[2] ; Dong,Liao ^[3] ; Ying,Li ^[4] ; Zhengyu,Li ^[4] ; Yuanru,Zhao ^[5] ; Xiaobo,Li ^[6] ; Manli,Dong ^[7]

作者单位： Department of General Practice, The First People's Hospital of Yunnan Province, Kunming, Yunnan, China. ^[1] Department of The Third outpatient, The First People's Hospital of Yunnan Province, Kunming, Yunnan, China. ^[2] Department of Ultrasound, Yunnan Geriatric Hospital, Kunming, Yunnan, China. ^[3] Department of Rehabilitation Medicine, The First People's Hospital of Yunnan Province, Kunming, Yunnan, China. ^[4] Department of Laboratory Medicine, Yunnan Xinkunhua Hospital, Kunming, Yunnan, China. ^[5] Department of Geriatric Medicine, The First People's Hospital of Yunnan Province, Kunming, Yunnan, China. Electronic address: lixiaobo783@outlook.com.com. ^[6] Department of Rehabilitation Medicine, The First People's Hospital of Yunnan Province, Kunming, Yunnan, China. Electronic address: Dongmanli7736@163.com. ^[7]

关键词 Alzheimer’s disease Apoptosis MicroRNA-142–5p Protein kinase B signaling pathway Protein tyrosine phosphatase nonreceptor type 1