作者：
Zhaohui,Li [1]
;
Shihua,Li [2]
;
Gen,Zhang [1]
;
Weiyu,Peng [1]
;
Zhen,Chang [1]
;
Xue,Zhang [3]
;
Zheng,Fan [4]
;
Yan,Chai [4]
;
Feiran,Wang [1]
;
Xin,Zhao [1]
;
Dedong,Li [1]
;
Rong,Zhang [5]
;
Zhanlong,He [1]
;
Weiwei,Zou [1]
;
Ke,Xu [3]
;
Wenwen,Lei [1]
;
Peipei,Liu [6]
;
Junfeng,Hao [7]
;
Jingjing,Zhang [4]
;
Litao,Sun [8]
;
Guizhen,Wu [8]
;
Shuguang,Tan [8]
;
George Fu,Gao [9]
;
Feng,Gao [10]
;
Yan,Wu [10]
作者单位：
CAS Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
[1]
University of Chinese Academy of Sciences, Beijing, China.
[2]
College of Veterinary Medicine, China Agricultural University, Beijing, China.
[3]
Department of Pathogen Microbiology, School of Basic Medical Sciences, Capital Medical University, Beijing, China.
[4]
School of Life Sciences, University of Science and Technology of China, Hefei, Anhui, China.
[5]
Laboratory of Animal Infectious Diseases, College of Animal Sciences and Veterinary Medicine, Guangxi University, Nanning, China.
[6]
Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, Yunnan, China.
[7]
NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
[8]
Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
[9]
School of Public Health (Shenzhen), Sun Yat-sen University, Guangzhou, China.
[10]
CAS Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China. tansg@im.ac.cn.
[11]
CAS Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China. gaof@im.ac.cn.
[12]
Laboratory of Protein Engineering and Vaccines, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China. gaofeng@tib.cas.cn.
[13]
Laboratory of Structural Biology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China. gaofeng@tib.cas.cn.
[14]
CAS Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China. wuyan@ccmu.edu.cn.
[15]
Department of Pathogen Microbiology, School of Basic Medical Sciences, Capital Medical University, Beijing, China. wuyan@ccmu.edu.cn.
[16]
主题词
动物(Animals);抗体, 双特异性(Antibodies, Bispecific);抗体, 单克隆(Antibodies, Monoclonal);抗体, 中和(Antibodies, Neutralizing);抗体, 病毒(Antibodies, Viral);克隆, 分子(Cloning, Molecular);疾病模型, 动物(Disease Models, Animal);剂量效应关系, 免疫(Dose-Response Relationship, Immunologic);表位(Epitopes);人类(Humans);猕猴(Macaca mulatta);小鼠(Mice);中和试验(Neutralization Tests);蛋白质工程(Protein Engineering);构效关系(Structure-Activity Relationship)
DOI
10.1038/s41590-022-01138-w
PMID
35228696
发布时间
2022-10-22
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