Synthetic mammalian signaling circuits for robust cell population control.

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第一作者： Yitong,Ma

第一单位： Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

作者： Yitong,Ma ^[1] ; Mark W,Budde ^[2] ; Michaëlle N,Mayalu ^[3] ; Junqin,Zhu ^[4] ; Andrew C,Lu ^[1] ; Richard M,Murray ^[5] ; Michael B,Elowitz ^[6]

作者单位： Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA. ^[1] Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA; Primordium Labs, Arcadia, CA 91006, USA. ^[2] Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA 91125, USA. ^[3] Department of Biology, Stanford University, Stanford, CA 94305, USA. ^[4] Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA; Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA 91125, USA. ^[5] Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA; Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA 91125, USA; Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA 91125, USA. Electronic address: melowitz@caltech.edu. ^[6]

关键词 auxin cell population control mammalian synthetic biology paradoxical control quorum sensing synthetic circuits synthetic signaling