Cadaverine Is a Switch in the Lysine Degradation Pathway in <i>Pseudomonas aeruginosa</i> Biofilm Identified by Untargeted Metabolomics.

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作者： Abigail,Leggett ^[1] ; Da-Wei,Li ^[2] ; Devin,Sindeldecker ^[3] ; Amelia,Staats ^[4] ; Nicholas,Rigel ^[3] ; Lei,Bruschweiler-Li ^[5] ; Rafael,Brüschweiler ^[3] ; Paul,Stoodley ^[6]

作者单位： Ohio State Biochemistry Program, The Ohio State University, Columbus, OH, United States. ^[1] Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH, United States. ^[2] Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States. ^[3] Campus Chemical Instrument Center, The Ohio State University, Columbus, OH, United States. ^[4] Biomedical Sciences Graduate Program, The Ohio State University, Columbus, OH, United States. ^[5] Department of Microbiology, The Ohio State University, Columbus, OH, United States. ^[6] Department of Biological Chemistry and Pharmacology, The Ohio State University, Columbus, OH, United States. ^[7] Department of Orthopaedics, The Ohio State University, Columbus, OH, United States. ^[8] National Biofilm Innovation Centre (NBIC) and National Centre for Advanced Tribology at Southampton (nCATS), Mechanical Engineering, University of Southampton, Southampton, United Kingdom. ^[9]

关键词 NMR-based metabolomics Pseudomonas aeruginosa bacterial metabolism biofilm cadaverine lysine degradation pathway