换一批
第一作者：
Hongjie,Li
第一单位：
Howard Hughes Medical Institute, Department of Biology, Stanford University, Stanford, CA 94305, USA.;Huffington Center on Aging, Baylor College of Medicine, Houston, TX 77030, USA.;Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
作者：
Hongjie,Li [1]
;
Jasper,Janssens [2]
;
Maxime,De Waegeneer [2]
;
Sai Saroja,Kolluru [3]
;
Kristofer,Davie [4]
;
Vincent,Gardeux [5]
;
Wouter,Saelens [5]
;
Fabrice P A,David [6]
;
Maria,Brbić [7]
;
Katina,Spanier [2]
;
Jure,Leskovec [7]
;
Colleen N,McLaughlin [8]
;
Qijing,Xie [8]
;
Robert C,Jones [3]
;
Katja,Brueckner [9]
;
Jiwon,Shim [10]
;
Sudhir Gopal,Tattikota [11]
;
Frank,Schnorrer [12]
;
Katja,Rust [13]
;
Todd G,Nystul [14]
;
Zita,Carvalho-Santos [15]
;
Carlos,Ribeiro [15]
;
Soumitra,Pal [16]
;
Sharvani,Mahadevaraju [17]
;
Teresa M,Przytycka [16]
;
Aaron M,Allen [18]
;
Stephen F,Goodwin [18]
;
Cameron W,Berry [19]
;
Margaret T,Fuller [19]
;
Helen,White-Cooper [20]
;
Erika L,Matunis [21]
;
Stephen,DiNardo [22]
;
Anthony,Galenza [23]
;
Lucy Erin,O'Brien [23]
;
Julian A T,Dow [24]
;
FCA Consortium§ [25]
;
Heinrich,Jasper [17]
;
Brian,Oliver [11]
;
Norbert,Perrimon [5]
;
Bart,Deplancke [3]
;
Stephen R,Quake [8]
;
Liqun,Luo [2]
;
Stein,Aerts [26]
;
Devika,Agarwal [27]
;
Yasir,Ahmed-Braimah [28]
;
Michelle,Arbeitman [29]
;
Majd M,Ariss [9]
;
Jordan,Augsburger [30]
;
Kumar,Ayush [31]
;
Catherine C,Baker [32]
;
Torsten,Banisch [33]
;
Katja,Birker [33]
;
Rolf,Bodmer [31]
;
Benjamin,Bolival [31]
;
Susanna E,Brantley [34]
;
Julie A,Brill [35]
;
Nora C,Brown [35]
;
Norene A,Buehner [25]
;
Xiaoyu Tracy,Cai [15]
;
Rita,Cardoso-Figueiredo [36]
;
Fernando,Casares [37]
;
Amy,Chang [38]
;
Thomas R,Clandinin [3]
;
Sheela,Crasta [39]
;
Claude,Desplan [40]
;
Angela M,Detweiler [15]
;
Darshan B,Dhakan [41]
;
Erika,Donà [37]
;
Stefanie,Engert [2]
;
Swann,Floc'hlay [42]
;
Nancy,George [37]
;
Amanda J,González-Segarra [43]
;
Andrew K,Groves [23]
;
Samantha,Gumbin [44]
;
Yanmeng,Guo [31]
;
Devon E,Harris [45]
;
Yael,Heifetz [46]
;
Stephen L,Holtz [47]
;
Felix,Horns [48]
;
Bruno,Hudry [49]
;
Ruei-Jiun,Hung [44]
;
Yuh Nung,Jan [44]
;
Jacob S,Jaszczak [41]
;
Gregory S X E,Jefferis [40]
;
Jim,Karkanias [50]
;
Timothy L,Karr [25]
;
Nadja Sandra,Katheder [33]
;
James,Kezos [51]
;
Anna A,Kim [52]
;
Seung K,Kim [19]
;
Lutz,Kockel [53]
;
Nikolaos,Konstantinides [54]
;
Thomas B,Kornberg [55]
;
Henry M,Krause [23]
;
Andrew Thomas,Labott [37]
;
Meghan,Laturney [56]
;
Ruth,Lehmann [37]
;
Sarah,Leinwand [8]
;
Jiefu,Li [49]
;
Joshua Shing Shun,Li [44]
;
Kai,Li [44]
;
Ke,Li [44]
;
Liying,Li [44]
;
Tun,Li [5]
;
Maria,Litovchenko [44]
;
Han-Hsuan,Liu [49]
;
Yifang,Liu [57]
;
Tzu-Chiao,Lu [42]
;
Jonathan,Manning [9]
;
Anjeli,Mase [35]
;
Mikaela,Matera-Vatnick [31]
;
Neuza Reis,Matias [58]
;
Caitlin E,McDonough-Goldstein [40]
;
Aaron,McGeever [59]
;
Alex D,McLachlan [23]
;
Paola,Moreno-Roman [40]
;
Norma,Neff [18]
;
Megan,Neville [23]
;
Sang,Ngo [33]
;
Tanja,Nielsen [44]
;
Caitlin E,O'Brien [60]
;
David,Osumi-Sutherland [61]
;
Mehmet Neset,Özel [42]
;
Irene,Papatheodorou [44]
;
Maja,Petkovic [62]
;
Clare,Pilgrim [40]
;
Angela Oliveira,Pisco [37]
;
Carolina,Reisenman [23]
;
Erin Nicole,Sanders [63]
;
Gilberto,Dos Santos [37]
;
Kristin,Scott [23]
;
Aparna,Sherlekar [37]
;
Philip,Shiu [26]
;
David,Sims [40]
;
Rene V,Sit [64]
;
Maija,Slaidina [65]
;
Harold E,Smith [37]
;
Gabriella,Sterne [23]
;
Yu-Han,Su [66]
;
Daniel,Sutton [33]
;
Marco,Tamayo [40]
;
Michelle,Tan [15]
;
Ibrahim,Tastekin [67]
;
Christoph,Treiber [8]
;
David,Vacek [33]
;
Georg,Vogler [67]
;
Scott,Waddell [54]
;
Wanpeng,Wang [46]
;
Rachel I,Wilson [35]
;
Mariana F,Wolfner [31]
;
Yiu-Cheung E,Wong [8]
;
Anthony,Xie [49]
;
Jun,Xu [68]
;
Shinya,Yamamoto [40]
;
Jia,Yan [37]
;
Zepeng,Yao [23]
;
Kazuki,Yoda [44]
;
Ruijun,Zhu [69]
;
Robert P,Zinzen
作者单位：
Howard Hughes Medical Institute, Department of Biology, Stanford University, Stanford, CA 94305, USA.;Huffington Center on Aging, Baylor College of Medicine, Houston, TX 77030, USA.;Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
[1]
VIB-KU Leuven Center for Brain and Disease Research, KU Leuven, Leuven 3000, Belgium.;Laboratory of Computational Biology, Department of Human Genetics, KU Leuven, Leuven 3000, Belgium.
[2]
Department of Bioengineering, Stanford University, Stanford, CA, USA.;Department of Applied Physics, Stanford University, Stanford, CA, USA.;Chan Zuckerberg Biohub, San Francisco CA, USA.
[3]
VIB-KU Leuven Center for Brain and Disease Research, KU Leuven, Leuven 3000, Belgium.
[4]
Laboratory of Systems Biology and Genetics, Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.;Swiss Institute of Bioinformatics, CH-1015 Lausanne, Switzerland.
[5]
Laboratory of Systems Biology and Genetics, Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.;Swiss Institute of Bioinformatics, CH-1015 Lausanne, Switzerland.;Bioinformatics Competence Center, EPFL, Switzerland.
[6]
Chan Zuckerberg Biohub, San Francisco CA, USA.;Department of Computer Science, Stanford University, Stanford, CA 94305, USA.
[7]
Howard Hughes Medical Institute, Department of Biology, Stanford University, Stanford, CA 94305, USA.
[8]
Department of Cell and Tissue Biology, University of California, San Francisco, CA 94143, USA.
[9]
Department of Life Science, College of Natural Science, Hanyang University, 04763 Seoul, Republic of Korea.
[10]
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.;Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
[11]
Aix-Marseille University, CNRS, IBDM (UMR 7288), Turing Centre for Living Systems, 13009 Marseille, France.
[12]
Institute of Physiology and Pathophysiology, Department of Molecular Cell Physiology, Philipps-University, Marburg, Germany.;Department of Anatomy, University of California, San Francisco, CA 94143, USA.
[13]
Department of Anatomy, University of California, San Francisco, CA 94143, USA.
[14]
Behavior and Metabolism Laboratory, Champalimaud Research, Champalimaud Centre for the Unknown, Lisbon, Portugal.
[15]
National Center of Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.
[16]
Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Kidney and Digestive Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
[17]
Centre for Neural Circuits and Behaviour, University of Oxford, Oxford OX1 3SR, UK.
[18]
Department of Developmental Biology and Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.
[19]
Molecular Biosciences Division, Cardiff University, Cardiff CF10 3AX, UK.
[20]
Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
[21]
Perelman School of Medicine, The University of Pennsylvania, Philadelphia, PA 19104, USA.;The Penn Institute for Regenerative Medicine, Philadelphia, PA 19104, USA.
[22]
Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA.
[23]
Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK.
[24]
Immunology Discovery, Genentech, Inc., South San Francisco, CA 94080, USA.
[25]
MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DS, UK.
[26]
Department of Biology, Syracuse University, Syracuse, NY 13244 USA.
[27]
Biomedical Sciences Department, Florida State University, Tallahassee, FL, USA.
[28]
Department of Genetics, Harvard Medical School, Boston, MA, USA.
[29]
Department of Computer Science, Stanford University, Stanford, CA 94305, USA.
[30]
Department of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
[31]
Skirball Institute and HHMI, New York University Langone Medical Center, New York City, NY 10016, USA.
[32]
Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
[33]
Cell Biology Program, The Hospital for Sick Children (SickKids), Toronto, ON M5G 0A4, Canada.;Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada.
[34]
Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.
[35]
CABD (Andalusian Centre for Developmental Biology), CSIC-UPO-JA, Seville 41013, Spain.
[36]
Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
[37]
Department of Neurobiology, Stanford University, Stanford, CA 94305, USA.
[38]
Department of Biology, New York University, New York, New York 10003, USA.
[39]
Chan Zuckerberg Biohub, San Francisco CA, USA.
[40]
Neurobiology Division, MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.
[41]
European Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Wellcome Trust Genome Campus, Hinxton CB10 1SD, UK.
[42]
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.;Department of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA.
[43]
Department of Physiology, Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, CA, USA.;Howard Hughes Medical Institute, San Francisco, CA, USA.
[44]
The Hebrew University of Jerusalem, Jerusalem, Israel.
[45]
Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
[46]
Department of Bioengineering and Biophysics Graduate Program, Stanford University, Stanford, CA 94305, USA.
[47]
Université Côte d'Azur, CNRS, INSERM, iBV, France.
[48]
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
[49]
Biodesign Institute, Arizona State University, Tempe, AZ 85281, USA.
[50]
Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA.;University of California, Santa Barbara, CA 93106, USA.;Uppsala University, Sweden.
[51]
Department of Developmental Biology and Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.;Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
[52]
Institut Jacques Monod, Centre National de la Recherche Scientifique-UMR 7592, Université Paris Diderot, Paris, France.
[53]
Cardiovascular Research Institute, University of California, San Francisco, CA 94143, USA.
[54]
Donnelly Centre for Cellular and Biomolecular Research, Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 3E1, Canada.
[55]
Skirball Institute, Department of Cell Biology and HHMI, New York University Langone Medical Center, New York City, NY 10016.
[56]
Huffington Center on Aging, Baylor College of Medicine, Houston, TX 77030, USA.
[57]
Department of Biology, Syracuse University, Syracuse, NY, USA.;Department of Evolutionary Biology, University of Vienna, Vienna, Austria.
[58]
Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK.
[59]
European Bioinformatics Institute (EMBL/EBI), Wellcome Trust Genome Campus, Cambridge, UK.
[60]
Department of Biology, New York University, New York, NY 10003, USA.
[61]
Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3DY, UK.
[62]
The Biological Laboratories, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA.
[63]
Skirball Institute, Faculty of Medicine, New York University, New York, NY 10016.
[64]
Genomics Core, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, MD, USA.
[65]
Graduate Program in Genetics and Genomics, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030 USA.
[66]
Centre for Neural Circuits and Behaviour, University of Oxford, Tinsley Building, Mansfield Road, Oxford OX1 3TA, UK.
[67]
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.;Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.
[68]
Laboratory for Systems Biology of Neural Tissue Differentiation, Berlin Institute for Medical Systems Biology (BIMSB), Max Delbrueck Centre for Molecular Medicine (MDC) in the Helmholtz Association, Robert-Roessle-Strasse 12, 13125 Berlin, Germany.
[69]
医学主题词
动物(Animals);细胞核(Cell Nucleus);数据库, 遗传学(Databases, Genetic);果蝇蛋白质类(Drosophila Proteins);黑腹果蝇(Drosophila melanogaster);女(雌)性(Female);基因表达调控(Gene Expression Regulation);基因调控网络(Gene Regulatory Networks);基因, 昆虫(Genes, Insect);男(雄)性(Male);性征(Sex Characteristics);单细胞分析(Single-Cell Analysis);转录因子(Transcription Factors)
DOI
10.1126/science.abk2432
PMID
35239393
发布时间
2026-03-07
- 浏览3
Science (New York, N.Y.)
Science (New York, N.Y.)
eabk2432页
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