换一批
换一批Safety and efficacy of aspirin, unfractionated heparin, both, or neither during endovascular stroke treatment (MR CLEAN-MED): an open-label, multicentre, randomised controlled trial.
作者：
Wouter,van der Steen [1]
;
Rob A,van de Graaf [2]
;
Vicky,Chalos [3]
;
Hester F,Lingsma [4]
;
Pieter Jan,van Doormaal [5]
;
Jonathan M,Coutinho [6]
;
Bart J,Emmer [7]
;
Inger,de Ridder [8]
;
Wim,van Zwam [9]
;
H Bart,van der Worp [10]
;
Irene,van der Schaaf [11]
;
Rob A R,Gons [12]
;
Lonneke S F,Yo [13]
;
Jelis,Boiten [14]
;
Ido,van den Wijngaard [15]
;
Jeannette,Hofmeijer [16]
;
Jasper,Martens [17]
;
Wouter,Schonewille [18]
;
Jan Albert,Vos [19]
;
Anil Man,Tuladhar [20]
;
Karlijn F,de Laat [21]
;
Boudewijn,van Hasselt [22]
;
Michel,Remmers [23]
;
Douwe,Vos [24]
;
Anouk,Rozeman [25]
;
Otto,Elgersma [26]
;
Maarten,Uyttenboogaart [27]
;
Reinoud P H,Bokkers [28]
;
Julia,van Tuijl [29]
;
Issam,Boukrab [30]
;
René,van den Berg [7]
;
Ludo F M,Beenen [7]
;
Stefan D,Roosendaal [7]
;
Alida Annechien,Postma [9]
;
Menno,Krietemeijer [13]
;
Geert,Lycklama [31]
;
Frederick J A,Meijer [32]
;
Sebastiaan,Hammer [33]
;
Anouk,van der Hoorn [28]
;
Albert J,Yoo [34]
;
Dick,Gerrits [35]
;
Martine T B,Truijman [36]
;
Sanne,Zinkstok [37]
;
Peter J,Koudstaal [36]
;
Sanne,Manschot [14]
;
Henk,Kerkhoff [25]
;
Daan,Nieboer [4]
;
Olvert,Berkhemer [38]
;
Lennard,Wolff [5]
;
P Matthijs,van der Sluijs [5]
;
Henk,van Voorst [39]
;
Manon,Tolhuisen [39]
;
Yvo B W E M,Roos [6]
;
Charles B L M,Majoie [7]
;
Julie,Staals [8]
;
Robert J,van Oostenbrugge [8]
;
Sjoerd F M,Jenniskens [32]
;
Lukas C,van Dijk [33]
;
Heleen M,den Hertog [40]
;
Adriaan C G M,van Es [41]
;
Aad,van der Lugt [5]
;
Diederik W J,Dippel [36]
;
Bob,Roozenbeek [2]
;
MR CLEAN-MED investigators
作者单位：
Department of Neurology, Erasmus MC University Medical Center, Rotterdam, Netherlands; Department of Radiology and Nuclear Medicine, Erasmus MC University Medical Center, Rotterdam, Netherlands. Electronic address: w.vandersteen@erasmusmc.nl.
[1]
Department of Neurology, Erasmus MC University Medical Center, Rotterdam, Netherlands; Department of Radiology and Nuclear Medicine, Erasmus MC University Medical Center, Rotterdam, Netherlands.
[2]
Department of Neurology, Erasmus MC University Medical Center, Rotterdam, Netherlands; Department of Radiology and Nuclear Medicine, Erasmus MC University Medical Center, Rotterdam, Netherlands; Department of Public Health, Erasmus MC University Medical Center, Rotterdam, Netherlands.
[3]
Department of Public Health, Erasmus MC University Medical Center, Rotterdam, Netherlands.
[4]
Department of Radiology and Nuclear Medicine, Erasmus MC University Medical Center, Rotterdam, Netherlands.
[5]
Department of Neurology, Amsterdam University Medical Centers, location AMC, Amsterdam, Netherlands.
[6]
Department of Radiology & Nuclear Medicine, Amsterdam University Medical Centers, location AMC, Amsterdam, Netherlands.
[7]
Department of Neurology, Maastricht University Medical Centre, Cardiovascular Research Institute Maastricht, Maastricht, Netherlands.
[8]
Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre, Cardiovascular Research Institute Maastricht, Maastricht, Netherlands.
[9]
Department of Neurology and Neurosurgery, Brain Center, University Medical Center Utrecht, Utrecht, Netherlands.
[10]
Department of Radiology, Brain Center, University Medical Center Utrecht, Utrecht, Netherlands.
[11]
Department of Neurology, Catharina Hospital, Eindhoven, Netherlands.
[12]
Department of Radiology, Catharina Hospital, Eindhoven, Netherlands.
[13]
Department of Neurology, Haaglanden Medical Centre, The Hague, Netherlands.
[14]
Department of Neurology, Haaglanden Medical Centre, The Hague, Netherlands; Department of Radiology, Haaglanden Medical Centre, The Hague, Netherlands.
[15]
Department of Neurology, Rijnstate Hospital, Arnhem, Netherlands.
[16]
Department of Radiology and Nuclear Medicine, Rijnstate Hospital, Arnhem, Netherlands.
[17]
Department of Neurology, St Antonius Hospital, Nieuwegein, Netherlands.
[18]
Department of Radiology, St Antonius Hospital, Nieuwegein, Netherlands.
[19]
Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, Netherlands.
[20]
Department of Neurology, HagaZiekenhuis, The Hague, Netherlands.
[21]
Department of Radiology, Isala, Zwolle, Netherlands.
[22]
Department of Neurology, Amphia Hospital, Breda, Netherlands.
[23]
Department of Radiology, Amphia Hospital, Breda, Netherlands.
[24]
Department of Neurology, Albert Schweitzer Hospital, Dordrecht, Netherlands.
[25]
Department of Radiology, Albert Schweitzer Hospital, Dordrecht, Netherlands.
[26]
Department of Neurology, University Medical Center Groningen, Groningen, Netherlands; Department of Radiology, Medical Imaging Center, University Medical Center Groningen, Groningen, Netherlands.
[27]
Department of Radiology, Medical Imaging Center, University Medical Center Groningen, Groningen, Netherlands.
[28]
Department of Neurology, Elisabeth-TweeSteden Hospital, Tilburg, Netherlands.
[29]
Department of Radiology, Elisabeth-TweeSteden Hospital, Tilburg, Netherlands.
[30]
Department of Radiology, Haaglanden Medical Centre, The Hague, Netherlands.
[31]
Department of Medical Imaging, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, Netherlands.
[32]
Department of Radiology, HagaZiekenhuis, The Hague, Netherlands.
[33]
Texas Stroke Institute, Dallas-Fort Worth, TX, USA.
[34]
Medisch Spectrum Twente, Enschede, Netherlands.
[35]
Department of Neurology, Erasmus MC University Medical Center, Rotterdam, Netherlands.
[36]
Tergooi, Hilversum, Netherlands.
[37]
Department of Neurology, Erasmus MC University Medical Center, Rotterdam, Netherlands; Department of Radiology and Nuclear Medicine, Erasmus MC University Medical Center, Rotterdam, Netherlands; Department of Radiology & Nuclear Medicine, Amsterdam University Medical Centers, location AMC, Amsterdam, Netherlands.
[38]
Department of Radiology & Nuclear Medicine, Amsterdam University Medical Centers, location AMC, Amsterdam, Netherlands; Department of Biomedical Engineering and Physics, Amsterdam University Medical Centers, location AMC, Amsterdam, Netherlands.
[39]
Department of Neurology, Isala, Zwolle, Netherlands.
[40]
Department of Radiology, Leiden University Medical Center, Leiden, Netherlands.
[41]
主题词
成年人(Adult);阿司匹林(Aspirin);脑缺血(Brain Ischemia);肝素(Heparin);人类(Humans);磁共振成像(Magnetic Resonance Imaging);卒中(Stroke);治疗结果(Treatment Outcome)
DOI
10.1016/S0140-6736(22)00014-9
PMID
35240044
发布时间
2022-04-06
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Lancet (London, England)
Lancet (London, England)
1059-1069页
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