Determination of optimal regularization factor in Bayesian penalized likelihood reconstruction of brain PET images using [<sup>18</sup> F]FDG and [<sup>11</sup> C]PiB.

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第一作者： Kei,Wagatsuma

第一单位： School of Allied Health Sciences, Kitasato University, Minami-ku, Sagamihara, Kanagawa, Japan.

作者： Kei,Wagatsuma ^[1] ; Kenta,Miwa ^[2] ; Yuto,Kamitaka ^[3] ; Emiya,Koike ^[2] ; Tensho,Yamao ^[4] ; Tokiya,Yoshii ^[3] ; Rinya,Kobayashi ^[4] ; Shogo,Nezu ^[5] ; Yuta,Sugamata ^[6] ; Noriaki,Miyaji ^[6] ; Etsuko,Imabayashi ^[7] ; Kenji,Ishibashi ^[8] ; Jun,Toyohara ^[2] ; Kenji,Ishii ^[2]

作者单位： School of Allied Health Sciences, Kitasato University, Minami-ku, Sagamihara, Kanagawa, Japan. ^[1] Research Team for Neuroimaging, Tokyo Metropolitan Institute of Gerontology, Sakae-cho, Itabashi-ku, Tokyo, Japan. ^[2] Department of Radiological Sciences, School of Health Sciences, Fukushima Medical University, Sakaemachi, Fukushima, Fukushima, Japan. ^[3] Department of Radiology, Fukushima Medical University Hospital, Hikarigaoka, Fukushima, Fukushima, Japan. ^[4] Department of Radiology, Tokai University Hospital, Shimokasuya, Isehara-shi, Kanagawa, Japan. ^[5] Department of Radiological Sciences, School of Health Sciences, International University of Health and Welfare, Kitakanemaru, Ohtawara, Tochigi, Japan. ^[6] Department of Nuclear Medicine, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Ariake, Koto-ku, Tokyo, Japan. ^[7] Department of Molecular Imaging and Theranostics, Institute for Quantum Medical Science, Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Anagawa, Inage-ku, Chiba, Japan. ^[8]

关键词 Alzheimer disease Bayesian penalized likelihood Q.Clear amyloid PET