Clinical grade lentiviral vector purification and quality control requirements.

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作者： Ruina,Shi ^[1] ; Shenghua,Jia ^[2] ; Huwei,Liu ^[3] ; Honggang,Nie ^[4]

作者单位： Quality Department, Beijing Imunopharm Pharmaceuticals Co., Ltd., Beijing, P. R. China. ^[1] Research and Development Center, Beijing Imunopharm Pharmaceuticals Co., Ltd., Beijing, P. R. China. ^[2] College of Life Sciences, Wuchang University of Technology, Wuhan, P. R. China. ^[3] Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing, P. R. China. ^[4] Analytical Instrumental Center, Peking University, Beijing, P. R. China. ^[5]

关键词 downstream processing gene therapy lentiviral vectors purification quality control

主题词遗传载体(Genetic Vectors);慢病毒属(Lentivirus);质量控制(Quality Control)

DOI 10.1002/jssc.202100937

PMID 35247228

发布时间 2022-06-29

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