Prophylactic or therapeutic administration of Holarrhena floribunda hydro ethanol extract suppresses complete Freund's adjuvant-induced arthritis in Sprague-Dawley rats.

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作者： Stephen,Antwi ^[1] ; Daniel,Oduro-Mensah ^[2] ; Jerry,Asiedu-Larbi ^[3] ; Ebenezer,Oduro-Mensah ^[4] ; Olga,Quasie ^[3] ; Clara,Lewis ^[5] ; David,Darko-Obiri ^[6] ; Augustine,Ocloo ^[7] ; Laud Kenneth,Okine ^[7]

作者单位： Department of Pharmacology/Toxicology, Centre for Plant Medicine Research, P. O. Box 73, Mampong, Akuapem, Ghana.;Department of Pharmacology, Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana. ^[1] Department of Biochemistry, Cell and Molecular Biology, College of Basic and Applied Sciences, University of Ghana, P. O. Box LG 54, Accra, Ghana. danoduro-mensah@ug.edu.gh.;West African Centre for Cell Biology of Infectious Pathogens, College of Basic and Applied Sciences, University of Ghana, Accra, Ghana. danoduro-mensah@ug.edu.gh. ^[2] Department of Pharmacology/Toxicology, Centre for Plant Medicine Research, P. O. Box 73, Mampong, Akuapem, Ghana. ^[3] Ga-East Municipal Hospital, Kwabenya, Accra, Ghana. ^[4] Clinical Research Department, Centre for Plant Medicine Research, P. O. Box 73, Mampong, Akuapem, Ghana. ^[5] Department of Pharmacology, Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana. ^[6] Department of Biochemistry, Cell and Molecular Biology, College of Basic and Applied Sciences, University of Ghana, P. O. Box LG 54, Accra, Ghana.;West African Centre for Cell Biology of Infectious Pathogens, College of Basic and Applied Sciences, University of Ghana, Accra, Ghana. ^[7]

关键词 Arthritis Cytokines Holarrhena floribunda Immunomodulation Inflammation

DOI 10.1186/s12950-022-00301-2

PMID 35248062

发布时间 2024-08-24

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