首页> Journal of dairy science> Overactivation of hepatic mechanistic target of rapamycin kinase complex 1 (mTORC1) is associated with low transcriptional activity of transcription factor EB and lysosomal dysfunction in dairy cows with clinical ketosis.

Overactivation of hepatic mechanistic target of rapamycin kinase complex 1 (mTORC1) is associated with low transcriptional activity of transcription factor EB and lysosomal dysfunction in dairy cows with clinical ketosis.

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第一作者： Zhiyuan,Fang

第一单位： Key Laboratory of Zoonosis, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun 130062, Jilin, China.

作者： Zhiyuan,Fang ^[1] ; Xinwei,Li ^[1] ; Shu,Wang ^[1] ; Qianming,Jiang ^[2] ; Juan J,Loor ^[2] ; Xiuhuan,Jiang ^[1] ; Lingxue,Ju ^[1] ; Hao,Yu ^[1] ; Taiyu,Shen ^[1] ; Men,Chen ^[1] ; Yuxiang,Song ^[1] ; Zhe,Wang ^[1] ; Xiliang,Du ^[3] ; Guowen,Liu ^[4]

作者单位： Key Laboratory of Zoonosis, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun 130062, Jilin, China. ^[1] Mammalian NutriPhysioGenomics, Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana 61801. ^[2] Key Laboratory of Zoonosis, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun 130062, Jilin, China. Electronic address: duxiliang@jlu.edu.cn. ^[3] Key Laboratory of Zoonosis, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun 130062, Jilin, China. Electronic address: liuguowen2008@163.com. ^[4]

关键词 autophagy liver injury mechanistic target of rapamycin kinase complex 1 (mTORC1)steatosis transcription factor EB (TFEB)